PhD student – 38 hours p/w –

We are looking for PhD student in the group of Dr. Francesca Mattiroli at the Hubrecht Institute. The successful candidate will work in a collaborative project between the Mattiroli lab and the lab of Prof. Jeroen Bakkers, aimed at studying how small chromatin-binding proteins affect gene expression, epigenome organization and cell cycle progression. These proteins have been identified to have a key role in heart regeneration in Zebrafish, the candidate will reveal the molecular mechanisms at the basis of this function. The successful candidate will use human RPE-1 cells to determine the mechanism of action of such proteins, and they may later in the project use cardiomyocytes to validate such mechanisms in heart-relevant systems. The PhD student will use molecular and cell biology, genomics and proteomics approaches. An enthusiastic and collaborative work attitude, with good communication and organizational skills is a prerequisite for this position. Scientific curiosity, critical thinking and independence are at the basis of this PhD training. The position is open to candidates with a MSc degree. Previous training in cell biology and genomics is an advantage.

For questions please contact f.mattiroli@hubrecht.eu

About the Hubrecht Institute
The Hubrecht Institute is a research institute focused on molecular and developmental biology. Because of the dynamic character of the research, the institute has a variable number of research groups, around 20, that do fundamental, multidisciplinary research on healthy and diseased cells, tissues and organisms. The Hubrecht Institute is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW), situated on Utrecht Science Park. Since 2008, the institute is affiliated with the UMC Utrecht, advancing the translation of research to the clinic. The Hubrecht Institute has a partnership with the European Molecular Biology Laboratory (EMBL). For more information, visit www.hubrecht.eu.

Terms of employment
Depending on education and experience the minimum salary is € 3.059 and the maximum salary is € 3.881 gross per month for a full-time appointment (scale P cao Nederlandse Universiteiten/KNAW). This is exclusive of 8% vacation allowance, 8.3% year-end bonus, travel allowance, internet allowance, home working allowance and pension accrual with ABP.

The KNAW offers its staff an excellent package of secondary benefits. A package that meets the different needs of employees depending on their stage of life, lifestyle or career ambitions. For example, by working an extra two hours a week, it is possible to increase the number of days off from 29 to 41 days a year (with full-time employment).

For a complete overview of the terms of employment, please refer to the web page: werken bij de KNAW.

Applying for a Certificate of Good Conduct can be part of the employment procedure.

Diversity & Inclusion
The KNAW considers a working environment in which everyone feels welcome and appreciated of great importance. A working environment in which attention is paid to individual quality and where development opportunities are paramount. Together we strive for an inclusive culture in which we embrace differences. We would therefore like to invite candidates who want to contribute to this through their background and experience. In the event of equal suitability, preference will be given to the candidate who thus enhances diversity within the Academy.

We will not respond to any supplier enquiries based on this job advertisement.