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Key publications

Control of Epithelial Cell Migration and Invasion by the IKKβ- and CK1α-Mediated Degradation of RAPGEF2.
Magliozzi R, Low TW, Weijts BGMW, Cheng T, Spanjaard E, Mohammed S, van Veen A, Ovaa H, de Rooij J, Zwartkruis FJT, Bos JL, de Bruin A, Heck AJR, Guardavaccaro D.
Dev Cell. 2013 Dec 9;27(5):574-85.

 

Coupled activation and degradation of eEF2K regulates protein synthesis in response to genotoxic stress.
Kruiswijk F, Yuniati L, Magliozzi R, Low TW, Lim R, Bolder R, Mohammed S, Proud CG, Heck AJR, Pagano M, and Guardavaccaro D.
Science Signaling. 2012 Jun 5;5(227):ra40.
See also: Perspective

 

Control of chromosome stability by the βTrCP-REST-Mad2 axis.
Guardavaccaro D, Frescas D, Dorrello NV, Peschiaroli A, Multani AS, Cardozo T, Lasorella A, Iavarone A, Chang S, Hernando E, Pagano M.
Nature. 2008 Mar 20;452(7185):365-9.

 

Degradation of Id2 by the anaphase-promoting complex couples cell cycle exit and axonal growth.
Lasorella A, Stegmüller J, Guardavaccaro D, Liu G, Carro MS, Rothschild G, de la Torre-Ubieta L, Pagano M, Bonni A, Iavarone A.
Nature. 2006 Jul 27;442(7101):471-4.

 

Control of meiotic and mitotic progression by the F-box protein βTrCP1 in vivo.
Guardavaccaro D, Kudo Y, Boulaire J, Barchi M, Busino L, Donzelli M, Margottin-Goguet F, Jackson PK, Yamasaki L, Pagano M.
Dev Cell. 2003 Jun;4(6):799-812.