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The group of Prof. Dr. Wouter de Laat currently has a vacancy for a

full time (38 hours/week)

To work on: development of novel methods for genetic diagnostics

Description of the project: The technician will participate in one of two projects that both aim to develop novel methodologies for genetic diagnostics. The first project relates to Non-Invasive Prenatal Diagnosis. Aim of this project is to develop, in collaboration with biotech company Cergentis, the UMC Utrecht and various other Dutch academic medical centres an alternative method that enables offering pregnant couples carrying a severe genetic disease (cystic fibrosis, thalassemia, Duchenne, etc) a non-invasive bloodtest as an alternative to invasive amniocentesis or chorionic villus sampling. Interested candidates may want to refer to Vermeulen et al., AJHG 2017, where we show proof of principle of the method. Here, we will further refine the method, ultimately to allow implementation in routine diagnostics. The second project is in collaboration with biotech company GenDx and aims to develop novel methods for HLA-typing. HLA-typing is crucial to find matched donor-recipient couples for organ and tissue transplantation. Both projects will be carried out in a team with and under supervision of a bioinformatician and a postdoc.

Requirements: We are seeking a (preferably experienced) technician, trained in molecular biology and genetics, with interest in technology development and with excellent technical skills. The candidate should be curious and motivated to work in an ambitious and collaborative environment. The application should include a letter of motivation and a CV with two references.

Duration: 1 year with the possibility of an extension for one more year after positive evaluation.

Starting date: October 2020, or as soon as possible.

Salary: According to “CAO-Nederlandse Universiteiten” (CAO-NU), depending on experience scale 7 excluding 8% holiday allowance and an 8.3% year-end bonus. We offer an extensive package of fringe benefits.

Location: Utrecht Science Park, De Uithof.

Information: For additional information please contact Prof. Dr. Wouter de Laat, 

Interested? Please send your application including CV and contact details of two potential references, before August 26th, 2020 to, stating vacancy HUBR-2020-10 in the subject line.

Any acquisition further to this advertisement will not be appreciated.

Research group

de Laat group

Start date



Utrecht Science Park


Full time