Publications

van Rheenen group

2002:
van Rheenen J., Jalink K. (2002) Agonist-induced PIP2 hydrolysis inhibits cortical actin dynamics: Regulation at a global but not at a micrometer scale. Mol. Biol. Cell, 13: 3257-3267

van Rheenen J., Jalink K. (2002) Reconstruction of the axial pointspread function: Imaging subresolution membrane folds. Imaging and Microscopy, 4: 46-48.

van Rheenen J., Jalink K. (2002) Visualizing the surface profile of the basal membrane with high precision. Bioforum International, 6: 246-249.


2004:
van Rheenen J., Langeslag M., Jalink K. (2004) Correcting confocal acquisition to optimize imaging of fluorescence resonance energy transfer by sensitized emission. Biophys. J., 86: 2517-2529.


2005:
Danen E.H.J., van Rheenen J., Franken W., Jalink K., Sonnenberg A. (2005) Integrin-specific regulation of focal contact dynamics, polarization, and migratory strategy. J. Cell Biol., 169: 512-526.

Zwart W., Griekspoor A., Kuyl C., Marsman M., van Rheenen J., Janssen H., Calafat J., van Jam M., Janssen L., van Lith M., Jalink K., Neefjes J. (2005) Spatial seperation of HLA-DM/HLA-DR interactions within MIIC and phagosomal immune escape, Immunity, 22: 221-233.

van Rheenen J., Achame E.M., Janssen H., Calafat J., Jalink K. (2005) PIP2 in rafts: a critical re-evaluation, EMBO J., 24: 1664-1673.


2006:
Stroeken P.J., Alvarez B., van Rheenen J., Wijnands Y.M., Geerts D., Jalink K., Roos E. (2006) Integrin cytoplasmic domain-associated protein-1 (ICAP-1) interacts with the ROCK-I kinase at the plasma membrane. J Cell Physiol., 208(3):620-8.

Halstead J.R., van Rheenen J., Snel M.H., Meeuws S., Mohammed S., D'Santos S., Heck A.J., Jalink K., Divecha N. (2006) A role for PtdIns(4,5)P2 and PIP5Kalpha in regulating stress-induced apoptosis. Curr Biol., 16(18):1850-6.


2007:
Bins A*., van Rheenen J.*$, Jalink K., Halstead J.R., Divecha N., Spencer D.M., Haanen J.B.A.G., Schumacher T.N.M. (2007) Schumacher Intravital imaging of fluorescent markers and FRET by DNA tattooing. BMC biotech.7:2. *corresponding author, $equal contribution

Kedrin D, van Rheenen J, Hernandez L, Condeelis J, Segall JE. (2007) Cell motility and cytoskeletal regulation in invasion and metastasis. J Mammary Gland Biol Neoplasia. 12(2-3): 143-52.

Wilhelmsen K, Litjens SH, Kuikman I, Margadant C, van Rheenen J, Sonnenberg A. (2007) Serine phosphorylation of the integrin beta4 subunit is necessary for epidermal growth factor receptor induced hemidesmosome disruption. Mol Biol Cell. 18(9): 3512-22.

van Rheenen J, Song X, van Roosmalen W, Cammer M, Chen X, Desmarais V, Yip SC, Backer JM, Eddy RJ, Condeelis JS. (2007) EGF-induced PIP2 hydrolysis releases and activates cofilin locally in carcinoma cells. J Cell Biol., 179(6): 1247-59. Highlighted in Nat. Rev. Mol. Cell Biol., 9(2):91.


2008:
van den Bout I, van Rheenen J, van Angelen AA, de Rooij J, Wilhelmsen K, Jalink K, Divecha N, Sonnenberg A. (2008) Investigation into the mechanism regulating MRP localization. Exp Cell Res., 314(2): 330-41.

Raja WK, Cady NC, Castracane J, Gligorijevic B, van Rheenen J, Condeelis JS. (2008) The NANIVID: a new device for cancer cell migration studies. Proceedings of SPIE (Society for Optical Engineering)., 6859, 68591M

Kedrin D, Gligorijevic B, Wyckoff J, Verkusha VV, Condeelis J, Segall JE, van Rheenen J. (2008). Intravital imaging of metastatic behavior through a mammary imaging window. Nature Methods, (12):1019-21.


2009:
Jalink K., van Rheenen J. FilterFRET: quantitative imaging of sensitized emission. (2009) Laboratory Techniques in Biochemistry & Molecular Biology: FRET and FLIM imaging techniques.

van Rheenen J, Condeelis J., and Michael Glogauer (2009) A common cofilin activity cycle in invasive tumor cells and inflammatory cells. J. Cell Sci. , 122 (Pt 3): 305-311

Gligorijevic B, Kedrin D, Segall JE, Condeelis J, van Rheenen J. (2009) Dendra2 photoswitching through the Mammary Imaging Window, J. Vis. Exp, Jun 5;(28). pii: 1278. doi: 10.3791/1278.

Wolf K, Alexander S, Schacht V, Coussens LM, von Andrian UH, van Rheenen J, Deryugina E, Friedl P. Collaen-based cell migratio models in vitro and in vivo (2009) Semin Cell Dev Bio

Oser M, Yamaguchi H, Mader CC, Bravo-Cordero JJ, Arias M, Chen X, Desmarais V, van Rheenen J, Koleske AJ, Condeelis J. Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation. (2009) J Cell Biol.  Aug 24;186(4):571-87.

Leyman S, Sidani M, Ritsma L, Waterschoot D, Eddy R, Dewitte D, Debeir O, Decaestecker C, Vandekerckhove J, van Rheenen J, Ampe C, Condeelis J, Van Troys M. Unbalancing the PI(4,5)P2-cofilin interaction impairs cell steering. (2009) Mol Biol Cell., Sep 9.


2010:
Jalink K, van Rheenen, J (2010) Nano-imaging of membrane topography affects interpretations in cell biology. Nat. Meth. 7:486.

Snippert HJ, van der Vlier LG, Sato T, van Es JH, van der Born M, Kroen-Veenboer C, Barker N, Klein AM, van Rheenen J, Simons BD, Clevers H. (2010) Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells, Cell, 143(1): 134-144


2011:
Zomer A, Beerling E, Vlug EJ, van Rheenen J. (2011) Real-time intravital imaging of cancer models. Clin Transl.Oncol. , 13(12):848-54.

Steller EJ, Ritsma L, Raats DA, Hoogwater FJ, Emmink BL, Govaert KM, Laoukili J, Borel Rinkes IH, van Rheenen J, Kranenburg O. (2011 )The death receptor CD95 activates the cofilin pathway to stimulate tumour cell invasion. EMBO reports , Sep 1;12(9):931-7

Beerling E, Ritsma L, Vrisekoop N, Derksen PW, van Rheenen J. (2011) Intravital microscopy: new insights into metastasis of tumors. J Cell Sci. , Feb 1;124(Pt 3):299-310.


2012:
Bonapace L, Wyckoff J, Oertner T, van Rheenen J, Junt T, Bentires-Alj M. (2012) If You Don't Look, You Won't See: Intravital Multiphoton Imaging of Primary and Metastatic Breast Cancer. J. Mammary Gland Biol Neoplasia. May 12.

Ritsma L, Ponsoein B, van Rheenen J (2012) Intravital imaging of cell signaling in mice. IntraVital, 1:1, 1-9.

Ritsma, L.*, Steller, E.J.A.*, Beerling, E., Loomans, C.J.M., Zomer, A., Gerlach, C., Vrisekoop, N., Seinstra, D., van Gurp, L., Schäfer, R., Raats, D.A., de Graaff, A. Schumacher, T.N., de Koning, E.J.P. Borel Rinkes, I.H., Kranenburg, O. van Rheenen, J. (2012) Intravital Microscopy Through an Abdominal Imaging Window Reveals a Pre-Micrometastasis Stage During Liver Metastasis. Sci Transl Med 4, 158ra145.

Arriotti S, Beltman JB, Chodaczek G, Hoekstra ME, van Beek AE, Gomez-Eerland R, Ritsma L, van Rheenen J, Maree AF, Zal T, de Boer RJ, Haanen JB, Schumacher TN (2012) Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen. Proc. Natl Acad Sci USA, Nov 27; 109(48): 19739-44.

Zomer A, Ellenbroek SIJ, Ritsma L, Beerling E, Vrisekoop N, van Rheenen J (2012) Intravital imaging of Cancer Stem Cell Plasticity in Mammary tumors. Stem Cells, Dec 7 [Epub ahead of print].

Ritsma L, Steller EJA, Ellenbroek SIJ, Kranenburg O, Borel Rinkes IHM, van Rheenen (in press) Surgical implantation of the Abdominal Imaging Window for intravital imaging. Nat Protoc.

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