Publications

Korswagen group

Ng, S.S., Mahmoudi, T., Danenberg, E., Bejaoui, I., de Lau, W., Korswagen, H.C., Schutte, M. and Clevers, H. (2009) Phosphatidylinositol 3-kinase signaling does not activate the Wnt cascade. J. Biol Chem., 284:35308-13.

Lorenowicz, M.L. and Korswagen, H.C. (2009) Sailing with the Wnt: charting the Wnt processing and secretion route. Exp. Cell Res., 315:2683-2689.

Wassmer, T., Attar, N., Harterink, M., van Weering, J.R.T., Trear, C.J., Oakley, J., Goud, B., Stephens, D.J., Verkade, P., Korswagen, H.C. and Cullen, P. (2009) The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network. Dev. Cell, 17:110-122.

Neumann, S., Coudreuse, D.Y., van der Westhuyzen, D.R., Eckhardt, E.R., Korswagen, H.C., Schmitz, G. and Sprong, H. (2009) Mammalian Wnt3a is released on lipoprotein particles. Traffic,10:334-343.

Yang, P.T., Lorenowicz, M., Silhankova, M., Coudreuse, D.Y.M., Betist, M.C. and Korswagen, H.C. (2008) Wnt signaling requires retromer dependent recycling of MIG-14/Wls in Wnt producing cells. Dev. Cell,14:4-6.

Silhankova, M. and Korswagen, H.C. (2007) Migration of neuronal cells along the anterior-posterior body axis of C. elegans: Wnts are in control. Curr. Opin. Genet. Dev., 17:320-325.

Holmes, A., Flett, A., Coudreuse, D., Korswagen, H.C. and Pettitt, J. (2007) C. elegans Disabled is required for cell-type specific endocytosis and is essential in animals lacking the AP-3 adaptor complex. J. Cell Sci. 120:2741-2751.

Oosterveen, T., Coudreuse, D.Y.M., Yang, P.T. Fraser, E., Bergsma, J., Dale, T.C. and Korswagen, H.C. (2007) Two functionally distinct Axin-like proteins regulate canonical Wnt signaling in C. elegans. Dev. Biol., 308:438-448.

Soete, G., Betist, M.C. and Korswagen, H.C. (2007) Regulation of Caenorhabditis elegans body size and male tail development by the novel gene lon-8. BMC Dev. Biol. 7:20.

Coudreuse, D.Y.M and Korswagen, H.C. (2007) The making of Wnt: new insights into Wnt maturation, sorting and secretion. Development, 134:3-12.

Korswagen, H.C. (2007) Wnt signaling in C. elegans:new insights into the regulation of POP-1/TCF-mediated activation and repression. Adv. Dev. Biol. 17:95-110.

Korswagen, H.C. (2006) Regulation of the Wnt/beta-catenin pathway by redox signaling. Dev. Cell, 10:687-688.

Coudreuse, D.Y.M, Roel, G., Betist, M.C., Destree, O. and Korswagen, H.C. (2006) Wnt gradient formation requires retromer function in Wnt producing cells. Science, 312:921-924.

Essers, M.A., de Vries-Smits, L.M.M., Barker, N., Polderman, P.E., Burgering, B.M.T. and Korswagen, H.C. (2005) Functional interaction between beta-catenin and FOXO in oxidative stress signaling. Science, 308:1181-1184.

Smit, L., Baas, A., Kuipers, J., Korswagen, H., van de Wetering, M. and Clevers, H. (2004) Wnt activates the Tak1/Nlk kinase pathway. J. Biol. Chem., 279:17232-40.

van der Linden, A.M., Moorman, C., Cuppen, E., Korswagen, H.C. and Plasterk, R.H.A. (2003) Hyperactivation of the G12-mediated signaling pathway in Caenorhabditis elegans induces a developmental growth arrest via protein kinase C. Curr. Biol., 13:516-521.

Korswagen, H.C. (2002) Canonical and non-canonical Wnt signalling pathways in C. elegans: variations on a common signalling theme. BioEssays 24:801-810.

Korswagen, H.C.*, Coudreuse, D.Y.M, Betist, M.C., van de Water, S., Zivkovic, D. and Clevers, H.C. (2002) The Axin-like protein PRY-1 is a negative regulator of a canonical Wnt pathway in C. elegans. Genes & Dev. 16:1291-1302 (*Corresponding author).

Gleason, J.E., Korswagen, H.C. and Eisenmann, D.E. (2002) Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C. elegans vulval induction. Genes & Dev. 16:1281-1290.

Korswagen, H.C.*, Herman, M.A. and Clevers, H.C. (2000) Distinct beta-catenins mediate adhesion and signalling functions in C. elegans. Nature 406:527-532 (*Corresponding author).

Korswagen, H.C., van der Linden, S.M. and Plasterk, R.H.A. (1998) G protein activation of the Caenorhabditis elegans adenylyl cyclase SGS-1 induces neuronal degeneration. EMBO J. 15:5059-5065.

Korswagen, H.C., Park, J.H., Ohshima, Y. and Plasterk, R.H.A. (1997) An activating mutation in a Caenorhabditis elegans Gs protein induces neural degeneration. Genes & Dev. 11:1493-1503.

Jonkers, J., Korswagen, H.C., Acton, D., Breuer, M. and Berns, A. (1997) Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas. EMBO J. 16:441-450.

Korswagen, H.C., Durbin, R.M., Smits, M.T. and Plasterk, R.H.A.P. (1996) Transposon Tc1-derived sequence-tagged sites in Caenorhabditis elegans as markers for gene mapping. Proc. Natl. Acad. Sci. USA 93:14680-14685.

Mendel, J.E., Korswagen, H.C., Liu, K.S., Hajdu-Cronin, Y.M., Simon, M.I., Plasterk, R.H.A.P. and Sternberg, P.W. (1995) Participation of the protein Go in multiple aspects of behavior in C. elegans. Science 267:1652-1655.

Book chapters
Korswagen, H.C. and Plasterk, R.H.A. (2001) Heterotrimeric G proteins. Encyclopedia of Genetics. Academic Press.

Korswagen, H.C. and Clevers, H.C. (2000) Activation and repression of Wingless/Wnt target genes by the TCF/LEF-1 family of transcription factors. Cold Spring Harbor Symposia on Quantitative Biology, Vol. LXIV:141-147

About the group leader