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Recent publications

Deschamps group


Simmini S., Bialecka M., Huch M., Kester L., van de Wetering M., Sato T., Beck F., van Oudenaarden A., Clevers H., and Deschamps J. (2014). Transformation of intestinal stem cells into gastric stem cells upon loss of transcription factor Cdx2. Nature Communications, In press.

Neijts R., Simmini S., Giuliani F., van Rooijen C. and Deschamps J., (2014). Region-specific Regulation of Posterior Axial Elongation During Vertebrate Embryogenesis. Dev. Dynamics 243, 88-98.

Bialecka M., Young T., Chuva de Sousa Lopes S., ten Berge D., Sanders A., Beck F. and Deschamps J. (2012). Cdx2 contributes to the expansion of the early germ cell population in the mouse. Developmental Biology 371, 227-234.

van Rooijen C., Simmini S., Bialecka M., Neijts R., van de Ven C., Beck F. and Deschamps J. (2012). Evolutionary conserved requirement of Cdx for post-occipital tissue emergence. Development 139, 2576-2583.

Stringer E.J., Duluc I., Saandi T., Davidson I., Bialecka M. Sato T., Barker N., Clevers H., Pritchard C., Winton D., Wright N.A., Freund J.N., Deschamps J. and Beck F (2012). Cdx2 determines the fate of postnatal intestinal endoderm. Development 139, 465-474.

Van de Ven C., Bialecka M., Neijts R., Young, T., Rowland J., Stringer E.,van Rooijen C, Meijlink F., Novoa A., Freund JN., Mallo M., Beck F. and Deschamps J. (2011). Concerted involvement of Hox/Cdx genes and Wnt signaling in morphogenesis of the caudal neural tube and cloacal derivatives from the posterior growth zone. Development 138, 3451-3462.

Bialecka M., Wilson V and Deschamps (2010). Cdx mutations causing posterior axial truncations do not impair the long term tissue progenitors in the embryonic posterior growth zone. Developmental Biology 347, 228-234.

Mallo M., Wellik D and Deschamps J. (2010). Hox genes as regional designers of the vertebrate body plan. Developmental Biology 344, 7-15.

Young, T., Rowland, J., van de Ven, C., Bialecka, M., Novoa, A., Carapuco, M., van Nes, J., de Graaff, W., Duluc, I., Freund, JN., Beck, F., Mallo, M. and Deschamps, J. (2009). Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos. Dev Cell 17, 516-526.

Young T., and Deschamps J. (2009) Hox and Cdx genes in axial extension and patterning in the mouse embryo. Curr. Topics in genetics and Development 88, 33-53.

Holstege J., de Graaff W., Hossaini, M., Cardone-Cardo., S., Jaarsma D., van den Akker, E. and Deschamps J. (2008) Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice. Proc. Natn. Acad. Sci USA 105, 6338-6343.

Deschamps J.,(2007) Ancestral and recently recruited global control of the Hox genes in development. Current Opin. Genet Dev . 17, 422-427.

Yu-ichi Fujimura, Kyo-ichi Isono, Miguel Vidal, Mitsuhiro Endoh, Hiroshi Kajita, Yoko Mizutani-Koseki, Yoshihiro Takihara, Maarten van Lohuizen, Arie Otte, Thomas Jenuwein, Jacqueline Deschamps, and Haruhiko Koseki (2006). Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8 . Development 133: 2371-2381

van Nes J, de Graaff W., Lebrin F., Gerhard, M., Beck F. and Deschamps J. (2006) The Cdx4 mutation affects axial development and reveals an essential role of Cdx genes in the ontogenesis of the placental labyrinth in mice. Development 133. 419-28.

Stern C., Charite J., Deschamps J. Duboule, D., Durston, A., Kmita M., Nicolas, JF., Palmeirim I., Smith J. and Wolpert L. (2006). Head-tail patterning of the vertebrate embryo: one, two or many unresolved problems? Int. J. Dev. Biol. 50, 3-15.

Deschamps J. and van Nes J. (2005) Developmental regulation of the Hox genes during axial morphogenesis in the mouse. Development 132, 2931-2942.

Chawengsaksophak K., de Graaff W., Rossant J., Deschamps J. and Beck F. (2004) Cdx2 is essential for axial elongation in mouse development. Proc. Natn. Acad. Scis USA. 101: 7641-7645.

Forlani, S., Lawson, K.A. and Deschamps, J. (2003) Acquisition of Hox codes during gastrulation and axial elongation in the mouse embryo. Development 130, 3807-3819.

Oosterveen, T, Nierderreither K., Dollé P., Chambon, P., Meijlink, F. and Deschamps J. (2003) Retinoids regulate the anterior boundaries of 5'Hoxb genes in posterior hindbrain. EMBO J., 22, 262-269

Van den Akker E., Forlani S., Chawengshaksophak K., de Graaff W., Beck F., Meyer B., and Deschamps J. (2002). Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation. Development, 129, 2181-2193.

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