Hubrecht publications

2012

Bialecka M, Cdx genes and the maintenance of tissue progenitors in the mouse, Thesis, Universiteit Utrecht, p 1-100

Blauw HM, Barnes CP, van Vught PW, van Rheenen W, Verheul M, Cuppen E, Veldink JH, van den Berg LH., SMN1 gene duplications are associated with sporadic ALS., Neurology. 2012 Mar 13;78(11):776-80.

Choorapoikayil S, Kuiper RV, de Bruin A, den Hertog J., Haploinsufficiency of the genes encoding the tumor suppressor Pten predisposes zebrafish to hemangiosarcoma., Dis Model Mech. 2012 Mar;5(2):241-7.

de Lau WB, Snel B, Clevers HC., The R-spondin protein family., Genome Biol. 2012 Mar 22;13(3):242.

de Pater E, Ciampricotti M, Priller F, Veerkamp J, Strate I, Smith K, Lagendijk AK, Schilling TF, Herzog W, Abdelilah-Seyfried S, Hammerschmidt M, Bakkers J., Bmp Signaling Exerts Opposite Effects on Cardiac Differentiation., Circ Res. 2012 Feb 17;110(4):578-87

de Wit E, de Laat W., A decade of 3C technologies: insights into nuclear organization., Genes Dev. 2012 Jan 1;26(1):11-24.

Gommans WM, Berezikov E., Controlling miRNA regulation in disease., Methods Mol Biol. 2012;822:1-18.

Gommans WM, Berezikov E., Sample preparation for small RNA massive parallel sequencing., Methods Mol Biol. 2012;786:167-78.

Harterink M, Korswagen HC., Dissecting the Wnt secretion pathway: key questions on the modification and intracellular trafficking of Wnt proteins., Acta Physiol (Oxf). 2012 Jan;204(1):8-16.

Huang, HY., Functional analysis of Tudor-domain-containing proteins in the zebrafish germline, Thesis, Universiteit Utrecht, p 1-153

Huveneers S, Oldenburg J, Spanjaard E, van der Krogt G, Grigoriev I, Akhmanova A, Rehmann H, de Rooij J., Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling., J Cell Biol. 2012 Mar 5;196(5):641-52.

Itsara A, Vissers LE, Steinberg KM, Meyer KJ, Zody MC, Koolen DA, de Ligt J, Cuppen E, Baker C, Lee C, Graves TA, Wilson RK, Jenkins RB, Veltman JA, Eichler EE., Resolving the breakpoints of the 17q21.31 microdeletion syndrome with next-generation sequencing., Am J Hum Genet. 2012 Apr 6;90(4):599-613.

Itzkovitz S, Blat IC, Jacks T, Clevers H, van Oudenaarden A., Optimality in the development of intestinal crypts., Cell. 2012 Feb 3;148(3):608-19.

Junker JP, van Oudenaarden A., When noisy neighbors are a blessing: analysis of gene expression noise identifies coregulated genes., Mol Cell. 2012 Feb 24;45(4):437-8.

Kamminga LM, Luteijn MJ, den Broeder MJ, Redl S, Kaaij LJ, Roovers EF, Ladurner P, Berezikov E, Ketting RF., Hen1 is required for oocyte development and piRNA stability in zebrafish., EMBO J. 2012 Jan 4;31(1):248.

Kuijk EW, van Tol LT, van de Velde H, Wubbolts R, Welling M, Geijsen N, Roelen BA., The roles of FGF and MAP kinase signaling in the segregation of the epiblast and hypoblast cell lineages in bovine and human embryos., Development. 2012 Mar;139(5):871-82.

Lander AD, Kimble J, Clevers H, Fuchs E, Montarras D, Buckingham M, Calof AL, Trumpp A, Oskarsson T., What does the concept of the stem cell niche really mean today?, BMC Biol. 2012 Mar 9;10:19.

Linsen SE, Cuppen E., Methods for small RNA preparation for digital gene expression profiling by next-generation sequencing., Methods Mol Biol. 2012;822:205-17.

Middelkoop TC, Williams L, Yang PT, Luchtenberg J, Betist MC, Ji N, van Oudenaarden A, Kenyon C, Korswagen HC., The thrombospondin repeat containing protein MIG-21 controls a left-right asymmetric Wnt signaling response in migrating C. elegans neuroblasts., Dev Biol. 2012 Jan 15;361(2):338-48.

Mokry M, Hatzis P, Schuijers J, Lansu N, Ruzius FP, Clevers H, Cuppen E., Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes., Nucleic Acids Res. 2012 Jan;40(1):148-58

Mul JD, van Boxtel R, Bergen DJ, Brans MA, Brakkee JH, Toonen PW, Garner KM, Adan RA, Cuppen E., Melanocortin Receptor 4 Deficiency Affects Body Weight Regulation, Grooming Behavior, and Substrate Preference in the Rat., Obesity (Silver Spring). 2012 Mar;20(3):612-21.

Munsky B, Neuert G, van Oudenaarden A, Using gene expression noise to understand gene regulation, Science. 2012 Apr 13;336(6078):183-7.

Ostergaard P, Simpson MA, Mendola A, Vasudevan P, Connell FC, van Impel A, Moore AT, Loeys BL, Ghalamkarpour A, Onoufriadis A, Martinez-Corral I, Devery S, Leroy JG, van Laer L, Singer A, Bialer MG, McEntagart M, Quarrell O, Brice G, Trembath RC, Schulte-, Mutations in KIF11 Cause Autosomal-Dominant Microcephaly Variably Associated with Congenital Lymphedema and Chorioretinopathy., Am J Hum Genet. 2012 Feb 10;90(2):356-62.

Poell JB., Functional screens for cancer-modulating microRNAs, Thesis, Universiteit Utrecht, p 1-152

Schasfoort RB, de Lau W, van der Kooi A, Clevers H, Engbers GH., Method for estimating the single molecular affinity., Anal Biochem. 2012 Feb 15;421(2):794-6.

Schepers A, Clevers H., Wnt signaling, stem cells, and cancer of the gastrointestinal tract., Cold Spring Harb Perspect Biol. 2012 Apr 1;4(4).

Stringer EJ, Duluc I, Saandi T, Davidson I, Bialecka M, Sato T, Barker N, Clevers H, Pritchard CA, Winton DJ, Wright NA, Freund JN, Deschamps J, Beck F., Cdx2 determines the fate of postnatal intestinal endoderm., Development. 2012 Feb;139(3):465-74.

Teklenburg G, Weimar CH, Fauser BC, Macklon N, Geijsen N, Heijnen CJ, Chuva de Sousa Lopes SM, Kuijk EW., Cell Lineage Specific Distribution of H3K27 Trimethylation Accumulation in an In Vitro Model for Human Implantation., PLoS One. 2012;7(3):e32701.

Vermaat JS, Nijman IJ, Koudijs MJ, Gerritse FL, Scherer S, Mokry M, Roessingh W, Lansu N, de Bruijn E, van Hillegersberg R, Van Diest PJ, Cuppen E, Voest EE., Primary colorectal cancers and their subsequent hepatic metastases are genetically different: implications for selection of patients for targeted treatment., Clin Cancer Res. 2012 Feb 1;18(3):688-99.