Hubrecht publications

2009

Adamovic, T., McAllister, D., Guryev, V., Wang, X., Andrae, J.W., Cuppen, E., Jacob, H.J., Sugg, S.L. (2009) Microalterations of inherently unstable genomic regions in rat mammary carcinomas as revealed by long oligonucleotide array-based comparative genomic hybridization. Cancer Res. 69: 5159-5167.

Alders, M., Hogan, B.M., Gjini, E., Salehl, F., al Gazali, L., Hennekam, E.A., Holmberg, E.E., Mannens, M.M., Mulder, M.F., Offerhaus, G.J., Prescott, T.E., Schroor, E.J., Verheij, J.B., Witte, M., Zwijnenburg, P.J., Vikkula, J.M., Schulte-Merker, S., Hennekam, R.C. (2009) Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans. Nat. Genet. (in press). Epub 22.11.09.

Bakkers, J., Verhoeven, M.C., Abdelilah-Seyfried, S. (2009) Shaping the zebrafish heart: from left-right axis specification to epithelial tissue morphogenesis. Dev. Biol. 330: 213-220.

Barker, N., van Es, J.H., Jaks, V., Kasper, M., Snippert, H., Toftgard, R., Clevers, H. (2008) Very long-term self-renewal of small intestine, colon and hair follicles from cycling Lgr5+ stem cells. Cold Spring Harb. Symp. Quant. Biol. (in press). Epub 06.11.08.

Barker, N., Ridgway, R.A., van Es, J.H., van de Wetering, M., Begthel, H., van den Born, M., Danenberg, E., Clarke, A.R., Sansom, O.J., Clevers, H. (2009) Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 457:608-611.

Begus-Nahrmann, Y., Lechel, A., Obenauf, A.C., Nalapareddy, K., Peit, E., Hoffmann, E., Schlaudraff, F., Liss, B., Schirmacher, P., Kestler, H., Danenberg, E., Barker, N., Clevers, H., Speicher, M.R., Rudolph, K.L. (2009) p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice. Nat. Genet. 41: 1138-1143.

Beqqali, A., van Eldik, W., Mummery, C., Passier, R. (2009) Human stem cells as a model for cardiac differentiation and disease. Cell. Mol. Life Sci. 66: 800-813.

Boersema, P.J., Foong, L.Y., Ding, V.M., Lemeer, S., van Breukelen, B., Philp, R., Boekhorst, J., Snel, B., den Hertog, J., Choo, A.B., Heck, A.J. (2009) In depth qualitative and quantitative profiling of tyrosine phosphrylation using a combination of phosphopeptide immune-affinity purification and stable isotope dimethyl labeling. Mol. Cell. Proteomics (in press). Epub 21.09.09

Boonen, R.A.C.M., van Tijn, P., Zivkovic, D. (2009) Wnt signaling in Alzheimer’s disease: up or down, that is the question. Ageing Res. Rev. 8: 71-82.

Brittijn, S.A., Duivesteijn, S.J., Belmamoune, M., Bertens, L.F.M., Bitter, W., de Bruijn, J.D., Champagne, D., Cuppen, E., Flik, G., Vandenbroucke-Grauls, C.M., Janssen, R.A.J., de Jong, I.M., de Kloet, E.R., Kros, A., Meijer, A.H., Metz, J.R., van der Sar, A.M., Schaaf, M.J.M., Schulte-Merker, S., Spaink, H.P., Tak, P.P., Verbeek, F.J., Vervoordeldonk, M.J., Vonk, F.F., Witte, F., Yuan, H., Richardson, M.K. (2009) Zebrafish development and regeneration: new tools for  biomedical research. Int. J. Dev. Biol. 53: 835-850.

Brouwer, K. (2009) DNA repair mechanisms in C. elegans. Thesis, Univ. Utrecht, pp. 1-128.

Bussmann, J. (2009) Genetic analysis and in vivo imaging of vascular development in the zebrafish. Thesis, Univ. Utrecht, pp. 1-100.

Chen, G., Korfhagen, T.R., Xu, Y., Kitzmiller, J., Wert, S.E., Maeda, Y., Gregorieff, A., Clevers, H., Whitsett, J.A. (2009) SPDEF is required for Mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production. J. Clin. Invest. 119: 2914-2924.

Claycomb, J.M., Batista, P.J., Pang, K.M., Gu, W., Vasale, J.J., van Wolfswinkel, J.C., Chaves, D.A., Shirayama, M., Mitani, S., Ketting, R.F., Conte Jr., D., Mello, C.C. (2009) The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation. Cell 139: 123-134.

Clevers, H. (2009) Eyeing up new Wnt pathway players. Cell 139: 227-229.

Clevers, H. (2009) Inflammatory bowel disease, stress, and the endoplasmic reticulum. N. Engl. J. Med. 360: 726-727.

Clevers, H. (2009) Searching for adult stem cells in the intestine. EMBO Mol. Med. 1: 255-259.

de Bruijn, E., Cuppen, E., Feitsma, H. (2009) Highly efficiënt ENU mutagenesis in zebrafish. Methods Mol. Biol. 546: 3-12.

den Broeder, M.J., van der Linde, H., Brouwer, J.R., Oostra, B.A., Willemsen, R., Ketting, R.F. (2009) Generation and characterization of fmr1 knockout zebrafish. PLoS One 4: e7910.

de Pater, E., Clijsters, L., Marques, S.R., Lin, Y.F., Garavito-Aguilar, Z.V., Yelon, D., Bakkers, J. (2009) Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heart. Development 136: 1633-1641.

de Wit, E., Linsen, S.E.V., Cuppen, E., Berezikov, E. (2009) Repertoire and evolution of miRNA genes in four divergent nematode species. Genome Res. 19: 2064-2074.

el Azzouzi, H. (2009) Peroxisome proliferators –activated receptor (PPAR) regulation in cardiac metabolism and disease. Thesis, Univ. Utrecht, pp. 1-128.

Engdahl, C., Jochems, C., Gustafsson, J.A., van der Saag, P.T., Carlsten, H., Lagerquist, M.K. (2009) In vivo activation of gene transcription via oestrogen response elements by a raloxifene analogue. J. Endocrinol. 203: 349-356.

Faro, A., Boj, S.F., Ambrosio, R., van den Broek, O., Korving, J., Clevers, H. (2009) T-cell factor 4 (tcf7l2) is the main effector of Wnt signaling during zebrafish intestine organogenesis. Zebrafish 6: 59-68.

Faro, A., Boj, S.F., Clevers, H. (2009) Fishing for intestinal cancer models: unraveling gastrointestinal homeostatis and tumorigenesis in zebrafish. Zebrafish (in press). Epub 22.11.09.

Fu, H., Cai, J., Clevers, H., Fast, E., Gray, S., Greenberg, R., Jain, M.K., Ma, Q., Qiu, M., Rowitch, D.H., Taylor, C.M., Stiles, C.D. (2009) A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J. Neurosci. 29: 11399-11408.

Gladka, M., el Azouzi, H., de Windt, L.J., da Costa Martins, P.A. (2009) Aquaporin 7: the glycerol aquaeductus in the heart. Cardiovasc. Res. 83: 3-4.

Gligorijevic, B., Kedrin, D., Segall, J.E., Condeelis, J., van Rheenen, J. (2009) Dendra2 photoswitching through the mammary imaging window. J. Vis. Exp. 28: 1278.

Gregorieff, A., Stange, D.E., Kujala, P., Begthel, H., van den Born, M., Korving, J., Peters, P.J., Clevers, H. (2009) The Ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium. Gastroenterology 137: 1333-1345.

Guryev, V., Cuppen, E. (2009) Next generation sequencing approaches in genetic rodent model systems to study functional effects of human genetic variation. FEBS Lett. 583: 1668-1173

Haegebarth, A., Clevers, H. (2009) Wnt signaling, Lgr5, and stem cells in the intestine and skin. Am. J. Pathol. 174: 715-721.

Hogan, B.M., Bos, F.L., Bussmann, J., Witte, M., Chi, N.C., Duckers, H., Schulte-Merker, S. (2009) cbe1 is required for embryonic lymphangiogenesis and venous sprouting. Nat. Genet. 41: 396-398.

Hogan, B.M., Herpers, R., Witte, M., Helotera, H., Alitalo, K., Duckers, H.J., Schulte-Merker, S. (2009) Vegfc/Flt4 signalling is suppressed by Dll4 in developing zebrafish intersegmental arteries. Development 136: 4001-4009.

Hollestelle, A., Nagel, J.H., Smid, M., Lam, S., Elstrodt, F., Wasielewski, M., Ng, S.S., French, P.J., Peeters, J.K., Rozendaal, M.J., Riaz, M., Koopman, D.G., ten Hagen, T.L., de Leeuw, B.H., Zwarthoff, E.C., Teunisse, A., van der Spek, P.J., Klijn, J.G., Dinjens, W.N., Ethier, S.P., Clevers, H., Jochemsen, A.G., den Bakker, M.A., Foekens, J.A., Martens, J.W., Schutte, M. (2009) Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines. Breast Cancer Res. Treat. (in press). Epub 11.07.09.

Homberg, J., Fleur, S.E., Cuppen, E. (2009) Serotonin transporter deficiency increases abdominal fat in female, but not male rats. Obesity (in press). Epub 14.05.09.

Homberg, J.R., Mul, J.D., de Wit, E., Cuppen, E. (2009) Complete knockout of the nociceptin/orphanin FQ receptor in the rat does not induce compensatory changes in mu, delta and kappa opioid receptors. Neuroscience 163: 308-315.

Houwing, S. (2009) Piwi-RNA complexes in the zebrafish germline. Thesis, Univ. Utrecht, pp. 1-134.

in der Rieden, P.M., Vilaspasa, F.L., Durston, A.J., Xwnt8 directly initiates expression of labial Hox genes. Dev. Dyn. (in press). Epub 21.07.09.

Itoh, F., Itoh, S., Carvalho, R.L.C., Adachi, T., Ema, M., Goumans, M.J., Larsson, J., Karlsson, S., Takahashi, S., Mummery, C.L., ten Dijke, P., Kato, M. (2009) Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation. Lab. Invest. 89: 800-810.

Jalink, K., van Rheenen, J. (2009) FilterFRET: quantitative imaging of sensitized emission. In: Laboratory techniques in biochemistry and molecular biology vol. 33: FRET and FLIM techniques. Ed. Gadella, T.W.J. Academic Press, Burlington, pp. 289-349.

Jansen, M., ten Klooster, J.P., Offerhaus, G.J., Clevers, H. (2009) LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism. Physiol. Rev. 89: 777-798.

Ketting, R.F. (2009) Semiconserved regulation of mesendoderm differentiation by microRNAs. Dev. Cell 16: 487-488.

Lau, N.C., Robine, N., Martin, R., Chung, W.J., Niki, Y., Berezikov, E., Lai, E.C. (2009) Abundant primary piRNAs, endo-siRNAs, and microRNAs in Drosophila ovary cell line. Genome Res. 19:1776-1785.

Leyman, S., Sidani, M., Ritsma, L., Watershoot, D., Eddy, R., Dewitte, D., Debeir, O., Daestecker, C. Vandekerckhove, J., van Rheenen, J., Ampe, C., Condeelis, J., van Troys, M. (2009) Unbalancing the phosphatidylinositol-4,5-bisphosphate-cofilin interaction impairs cell steering. Mol. Biol. Cell 20: 4509-4523.

Linsen, S.E.V., de Wit, E., Janssens, G., Heater, S., Chapman, L., Parkin, R.K., Fritz, B., Wyman, S.K., de Bruijn, E., Voest, E.E., Kuersten, S., Tewari, M., Cuppen, E. (2009) Limitations and possibilities of small RNA digital gene expression profiling. Nat. Methods 6: 474-476.

Lips, D.J., Barker, N., Clevers, H., Hennipman, A. (2009) The role of APC and beta-catenin in the aetiology of aggressive fibromatosis (desmoid tumors). Eur. J. Surg. Oncol. 35: 3-10.

Lorenowicz, M.J., Korswagen, H.C. (2009) Sailing with the Wnt: charting the Wnt processing and secretion route. Exp. Cell Res. 315: 2683-2689.

Louwers, M., Bader, R., Haring, M., van Driel, R., de Laat, W., Stam, M. (2009) Tissue- and expression level-specific chromatin looping at maize b1 epialleles. Plant Cell 21: 832-842.

Louwers, M., Splinter, E., van Driel, R., de Laat, W., Stam, M. (2009) Studying physical chromatin interactions in plants using chromosome conformation capture (3C). Nat. Protoc. 4: 216-229.

Mahmoudi, T., Li, V.S.W., Ng, S.S., Taouatas, N., Vries, R.G.J., Mohammed, S., Heck, A.J., Clevers, H. (2009) The kinase TNIK is an essential activator of Wnt target genes. EMBO J. 28: 3329-3340.

Marques, I.J., Weiss, F.U., Vlecken, D.H., Nitsche, C., Bakkers, J., Lagendijk, A.K., Partecke, L.I., Heidecke, C.D., Lerch, M.M., Bagowski, C.P. (2009) Metastatic behaviour of primary human tumours in zebrafish xenotransplantation model. BMC Cancer 9: 128.

Matondo, R.B., Punt, C., Homberg, J., Toussaint, M.J.M., Kisjes, R., Korporaal, S.J.A., Akkerman, J.W.N., Cuppen, E., de Bruin, A. (2009) Deletion of the serotonin transporter in rates disturbs serotonin homeostasis without impairing liver regeneration. Am J. Physiol. Gastrointest. Liver Physiol. 296: G963-G968.

Medina, P.P., Castillo, S.D., Blanco, S., Sanz-Garcia, M., Largo, C., Alvarez, S., Sokota, J., Gonzalez-Neira, A., Benitez, J., Clevers, H.C., Cigudosa, J.C., Lazo, P.A., Sanchez-Cespedes, M. (2009) The SRY-HMG box gene, SOX4, is a target of gene amplification at chromosome 6p in lung cancer. Hum. Mol. Genet. 18: 1343-1352.

Mul, J., Yi, C.X., van den Berg, S.A., Ruiter, M., Toonen, P., van der Elst, M., Voshol, P.J., Ellenbroek, B., Kalsbeek, A., la Fleur, S.E., Cuppen, E. (2009) Pmch expression during early development is critical for normal energy homeostasis. Am. J. Physiol. Endocrinol. Metab. (in press). Epub 24.11.09.

Neumann, S., Coudreuse, D.Y.M., van der Westhuyzen, D.R., Eckhardt, E.R.M., Korswagen, H.C., Schmitz, G., Sprong, H. (2009) Mammalian Wnt3a is released on lipoprotein particles. Traffic 10: 334-343.

Ng, S.S., Mahmoudi, T., Danenberg, E., Bejaoui, I.,  de Lau, W., Korswagen, H.C., Schutte, M., Clevers, H. (2009) Phosphatidylinositol 3-kinase (PI3K) signaling does not activate the Wnt cascade. J. Biol. Chem. (in press). Epub 22.10.09

Nijmeijer, R.M., Leeuwis, J.W., DeLisio, A., Mummery, C.L., Chuva de Sousa Lopes, S.M. (2009) Visceral endoderm induces specification of cardiomyocytes in mice. Stem Cell Res 3: 170-178.

Oser, M., Yamaguchi, H., Mader, C.C., Bravo-Cordero, .J.J., Arias, M., Chen, X., DesMarais, V., van Rheenen, J., Koleske, A.J., Condeelis, J. (2009) Cortactin regulates cofilin and N-WASp activities to control the stages of invadopodium assembly and maturation. J. Cell Biol. 186: 571-587.

Paridaen, J. (2009) Regulation of neural development and adult brain hoemostasis in the zebrafish. Thesis, Univ. Utrecht, pp. 1-172.

Paridaen, J.T.M.L., Danesin, C., Elas, A.T., van de Water, S., Houart, C., Zivkovic, D. (2009) Apc1-mediated antagonism of Wnt/beta-catenin signaling is required for retino-tectal pathfinding in the zebrafish. Zebrafish 6: 41-47.

Paridaen, J.T.M.L., Danesin, C., Elas, A.T., van de Water, S., Houart, C., Zivkovic, D. (2009) Apc1 isrequired for maintenance of local brain organizers and dorsal midbrain survival. Dev. Biol. 331:101-112.

Penttinen-Damdimopoulou, P., Power, K.A., Hurmerinta, T.T., Nurmi, T., van der Saag, P.T., Makela, S.I. (2009) Dietary sources of lignans and isoflavones modulate responses to estradiol in estrogen reporter mice. Mol. Nutr. Food Res. 53: 996-1006.

Pereira, F., Queiros, S., Gusmao, L., Nijman, I.J., Cuppen, E., Lenstra, J.A., Econogene Consortium, Davis, S.J.M., Nejmeddine, F., Amorim, A. (2009) Tracing the history of goat pastoralism: new clues from mitochondrial and Y chromosome DNA in North Africa. Mol. Biol. Evol. 26: 2765-2773.

Pontier, D.B., Kruisselbrink, E., Guryev, V., Tijsterman, M. (2009) Isolation of deletion alleles by G4 DNA-induced mutagenesis. Nat. Methods 6: 655-657.

Pontier, D.B., Tijsterman, M. (2009) A robust network of double-strand break repair pathways governs genome integrity during C. elegans development. Curr. Biol. 19: 1384-1388.

Roel, G., Gent, Y.Y.J., Peterson-Maduro, J., Verbeek, F.J., Destree, O. (2009) Lef1 plays a role in patterning the mesoderm and ectoderm in Xenopus tropicalis. Int. J. Dev. Biol. 53: 81-89.

Sato, T., Vries, R.G., Snippert, H.J., van de Wetering, M., Barker, N., Stange, D.E., van Es, J.H., Abo, A., Kujala, P., Peters, P.J., Clevers, H. (2009) Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459: 262-266.

Schwamborn, J.C., Berezikov, E., Knoblich, J.A. (2009) The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell 136: 913-925.

Simonis, M., Klous, P., Homminga, I., Galjaard, R.J., Rijkers, E.J., Grosveld, F., Meijerink, J.P.P., de Laat, W. (2009) High-resolution identification of balanced and complex chromosomal rearrangements by 4C technology. Nat. Methods 6: 837-842.

Smith, K.A., Joziasse, I.C., Chocron, S., van Dinther, M., Guryev, V., Verhoeven, M.C., Rehmann, H., van der Smagt, J.J., Doevendans, P.A., Cuppen, E., Mulder, B.J., ten Dijke, P., Bakkers, J. (2009) Dominant-negative ALK2 allele associates with congenital heart defects. Circulation 119: 3062-3069.

Smits, A.M., van Laake, L.W., den Ouden, K., Schreurs, C., Szuhai, K., van Echteld, C.J., Mummery, C.L., Doevendans, P.A., Goumans, M.J. (2009) Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium. Cardiovasc. Res. 83: 527-535.

Snippert, H.J., van Es, J.H., van den Born, M., Begthel, H., Stange, D.E., Barker, N., Clevers, H. (2009) Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine. Gastroenterology 136: 2187-2194.

Steiner, F.A., Okihara, K.L., Hoogstrate, S.W., Sijen, T., Ketting, R.F. (2009) RDE-1 slicer activity is required only for passenger-strand cleavage during RNAi in Caenorhabditis elegans. Nat. Struct. Mol. Biol. 16: 207-211.

Takada, S., Berezikov, E., Choi, Y.L., Yamashita, Y., Mano, H. (2009) Potential role of miR-29b in modulation of Dnmt3a and Dnmt3b expression in primordial germ cells of female mouse embryos. RNA 15: 1507-1514.

Tee, J.M., van Rooijen, C., Boonen, R., Zivkovic, D. (2009) Regulation of slow and fast muscle myofibrillogenesis by Wnt/beta-catenin and myostatin signaling. PLoS One 4: e5880

ten Klooster, J.P., Jansen, M., Yuan, J., Oorschot, V., Begthel, H., di Giacomo, V., Colland, F., de Koning, J., Maurice, M.M., Hornbeck, P., Clevers, H. (2009) Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex. Dev. Cell 16: 551-562.

van den Akker, W.M., Durston, A.J., Spaink, H.P. (2009) Identification of hoxb1b downstream genes: hoxb1b has a regulatory factor controlling transcriptional networks and cell movement during zebrafish gastrulation. Int. J. Dev. Biol. (in press). Epub 22.10.09.

van den Bos, R., Homberg, J., Gijsbers, E., den Heijer, E., Cuppen, E. (2009) The effect of COMT Val158 Met genotype on decision-making and preliminary findings on its interaction with the 5-HTTLPR in healthy animals. Neuropharmacology 56: 493-498.

van der Flier, L.G. (2009) Wnt target gene analysis in colorectal cancer and intestinal stem cells. Thesis, Univ. Utrecht, pp. 1-136.

van der Flier, L.G., Clevers, H. (2009) Stem cells, self-renewal, and differentiation in the intestinal epithelium. Annu. Rev. Physiol. 71: 241-260.

van der Flier, L.G., Haegebarth, A., Stange, D.E., van de Wetering, M., Clevers, H. (2009) OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells. Gastroenterology 137: 15-17.

van der Flier, L.G., van Gijn, M.E., Hatzis, P., Kujala, P., Haegebarth, A., Stange, D.E., Begthel, H., van den Born, M., Guryev, V., Oving, I., van Es, J.H., Barker, N., Peters, P.J., van de Wetering, M., Clevers, H. (2009) Transcription factor Achaete scute-like 2 controls intestinal stem cell fate. Cell 136: 903-912.

van Hoof, D., Munoz, J., Braam, S.R., Pinkse, M.W.H., Linding, R., Heck, A.J.R., Mummery, C.L., Krijgsveld, J. (2009) Phosphorylation dynamics during early differentiation of human embryonic stem cells. Cell Stem Cell 5: 214-226.

van Rheenen, J., Condeelis, J., Glogauer, M. (2009) A common cofilin activity cycle in invasive tumor cells and inflammatory cells. J. Cell Sci. 122: 305-311.

van Rooijen, E., Voest, E.E., Logister, I., Korving, J., Schwerte, T., Schulte-Merker, S., Giles, R.H., van Eeden, F.J. (2009) Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia. Blood 113: 6449-6460.

van Stralen, E., Leguit, R.J., Begthel, H., Michaux, L., Buijs, A., Lemmens, H., Scheiff, J.M., Doyen, C., Pierre, P., Forget, F., Clevers, H.C., Bast, B.J.E.G. (2009) Mafβ oncoprotein detected by immunohistochemistry as a higly sensitive and specific marker for the prognostic unfavorable t(14;20) (q32;q12) in multiple myeloma patients. Leukemia 23: 801-803.

van Stralen, E., van de Wetering, M., Agnelli, L., Neri, A., Clevers, H.C., Bast, B.J.E.G. (2009) Identification of primary MAFB target genes in multiple myeloma. Exp. Hematol. 37: 78-86.

van Wolfswinkel, J.C., Claycomb, J.M., Batista, P.J., Mello, C.C., Berezikov, E., Ketting, R.F. (2009) CDE-1 affects chromosome segregation through uridylation of CSR-1-bound siRNAs. Cell 139: 135-148.

Verhoeven, M. (2009) Bmp signaling is at the heart of vertebrate left-right symmetry. Thesis, Univ. Utrecht, pp. 1-132.

Voss, K., Stahl, S., Hogan, B.M., Reinders, J., Schleider, E., Schulte-Merker, S., Felbor, U. (2009) Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein. Human Mutat. 30: 1003-1011.

Vreugdenhil, E., Berezikov, E. (2009) Fine-tuning the brain: microRNAs. Front. Neuroendocrinol. (in press). Epub 13.08.09.

Wassmer, T., Attar, N., Harterink, M., van Weering, J.R.T., Traer, C.J., Oakley, J., Goud, B., Stephens, D.J., Verkade, P., Korswagen, H.C., Cullen, P.J. (2009) The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network. Dev. Cell 17: 110-122.

Wolf, K., Alexander, S., Schacht, V., Coussens, L.M., von Andrian, U.H., van Rheenen, J., Deryugina, E., Friedl, P. (2009) Collagen-based cell migration models in vitro and in vivo. Semin. Cell Dev. Biol. 20: 931-941.

Ye, F., Chen, Y., Hoang, T.N., Montgomery, R.L., Zhao, X., Bu, H., Hu, T., Taketo, M.M., van Es, J.H., Clevers, H., Hsieh, J., Bassel-Duby, R., Olson, E.N., Lu, Q.R. (2009) HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nature Neurosci. 12: 829-838.

Young, T. (2009) Role of Cdx and Hox genes in posterior axial extension in the mouse. Thesis, Univ. Utrecht, pp. 1-126.

Young, T., Rowland, J.E., van de Ven, C., Bialecka, M., Novoa, A., Carapuco, M., van Nes, J., de Graaff, W., Duluc, I., Freund, J.N., Beck, F., Mallo, M., Deschamps, J. (2009) Cdx and Hox genes differentially regulate posterior axial growth in mammalian embryos. (Dev. Cell 17: 516-526.