Hubrecht publications

2006-2008

2008
Aitman, T.J., Critser, J.K., Cuppen, E., Dominiczak, A., Fernandez-Suarez, X.M., Flint, J., Gauguier, D., Geurts, A.M., Gould, M., Harris, P.C., Holmdahl, R., Hubner, N., Izsvak, Z., Jacob, H.J., Kuramoto, T., Kwitek, A.E., Marrone, A., Mashimo, T., Moreno, C., Mullins, J., Mullins, L., Olsson, T., Pravenec, M., Riley, L., Saar, K., Serikawa, T., Shull, J.D., Szpirer, C., Twigger, S.N., Voigt, B., Worley, K. (2008) Progress and prospects in rat genetics: a community view. Nat. Genet. 40: 516-522.

Armand, A.S., Bourajjaj, M., Martinez-Martinez, S., el Azzouzi, H., da Costa Martins, P.A., Hatzis, P., Seidler, T., Redondo, J.M., de Windt, L.J. (2008) Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis. J. Biol. Chem. 283: 29004-29010.

Barker, N., van de Wetering, M., Clevers, H. (2008) The intestinal stem cell. Genes Dev. 22: 1856-1864.

Beqqali, A. (2008) Human embryonic stem cells as a model for cardiac gene discovery: from chip to chap. Thesis, Univ. Utrecht, pp. 1-154.

Bierhuizen, M.F.A., Boulaksil, M., van Stuijvenberg, L., van der Nagel, R., Jansen, A.T., Mutsaers, N.A.M., Yildirim, C., van Veen, T.A.B., de Windt, L.J., Vos, M.A., van Rijen, H.V.M. (2008) In calcineurin-induced cardiac hypertrophy expression of Nav1.5, Cx40 and Cx43 is reduced by different mechanisms. J. Mol. Cell. Cardiol. 45: 373-384.

Bispo de Jesus, M., Zambuzzi, W.F., Ruela de Sousa, R.R., Areche, C., Santos de Souza, A.C., Aoyama, H., Schmeda-Hirschmann, G., Rodriguez, J.A., Monteiro de Souza Brito, A.R., Peppelenbosch, M.P., den Hertog, J., de Paula, E., Ferreira, C.V. (2008) Ferruginol suppresses survival signaling pathways in androgen-independent human prostate cancer cells. Biochimie 90: 843-854.

Bodrikov, V., Sytnyk, V., Leshchyns’ka, I., den Hertog, J., Schachner, M. (2008) NCAM induces CaMKllα-mediated RPTPα phosphorylation to enhance its catalytic activity and neurite outgrowth. J. Cell Biol. 182: 1185-1200.

Bourajjaj, M. (2008) Nuclear factor of activated T cells (NFAT): key regulator of cardiac hypertrophy and skeletal muscle adaptation. Thesis, Univ. Utrecht, pp. 1-124.

Bourajjaj, M., Armand, A.S., da Costa Martins, P.A., Weijts, B., van der Nagel, R., Heeneman, S., Wehrens, X.H., de Windt, L.J. (2008) NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure. J. Biol. Chem. 283: 22295-22303.

Braam, S.R., Denning, C., Matsa, E., Young, L.E., Passier, R., Mummery, C.L. (2008) Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification. Nat. Protoc. 3: 1435-1443.

Braam, S.R., Denning, C., van den Brink, S., Kats, P., Hochstenbach, R., Passier, R., Mummery, C.L. (2008) Improved genetic manipulation of human embryonic stem cells. Nat. Methods 5: 389-392.

Braam, S.R., Zeinstra, L., Litjens, S., Ward-van Oostwaard, D., van den Brink, S., van Laake, L., Lebrin, F., Kats, P., Hochstenbach, R., Passier, R., Sonnenberg, A., Mummery, C.L. (2008) Recombinant vitronectin is a functionally defined substrate that supports human embryonic stem cell self renewal via αVβ5 integrin. Stem Cells 26: 2275-2265.

Burns, C.J., Zhang, J., Brown, E.C., van Bibber, A.M., van Es, J., Clevers, H., Ishikawa, T., Taketo, M.M., Vetter, M.L., Fuhrmann, S. (2008) Investigation of Frizzled-5 during embryonic neural development in mouse. Dev. Dyn. 237: 1614-1626.

Bussmann, J., Lawson, N., Zon, L., Schulte-Merker, S., Zebrafish Nomenclature Committee (2008) Zebrafish VEGF receptors: a guideline to nomenclature. PLoS Genet. 4: e1000064.

Cid, V.J., Rodriguez-Escudero, I., Andres-Pons, A., Roma-Mateo, C., Gil, A., den Hertog, J., Molina, M., Pulido, R. (2008) Assessment of PTEN tumor suppressor activity in nonmammalian models: the year of the yeast. Oncogene 27: 5431-5442.

Colak, D., Mori, T., Brill, M.S., Pfeifer, A., Falk, S., Deng, C., Monteiro, R., Mummery, C., Sommer, L., Gotz, M. (2008) Adult neurogenesis requires Smad4-mediated bone morphogenic protein signaling in stem cells. J. Neurosci. 28: 434-445.

da Costa Martins, P.A., Bourajjaj, M., Gladka, M., Kortland, M., van Oort, R.J., Pinto, Y.M., Molkentin, J.D., de Windt, L.J. (2008) Conditional Dicer gene deletion in the postnatal myocardium provokes spontaneous cardiac remodeling. Circulation 118: 1567-1576.

da Costa Martins, P.A., de Windt, L.J. (2008) Nix: the cardiac Styx between life and death. Circulation 117: 338-340.

Das, P.P., Bagijn, M.P., Goldstein, L.D., Woolford, J.R., Lehrbach, N.J., Sapetschnig, A., Buhecha, H.R., Gilchrist, M.J., Howe, K.L., Stark, R., Matthews, N., Berezikov, E., Ketting, R.F., Tavare, S., Miska, E.A. (2008) Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline. Mol. Cell 31: 79-90.

den Hertog, J., Ostman, A., Bohmer, F.D. (2008) Protein tyrosine phosphatases: regulatory mechanisms. FEBS J. 275: 831-847.

Deschamps, J. (2008) Tailored Hox gene transcription and the making of the thumb. Genes Dev. 22: 293-296.

Diks, S.H., Sartori da Silva, M.A., Hillebrands, J.L., Bink, R.J., Versteeg, H.H., van Rooijen, C., Brouwers, A., Chitnis, A.B., Peppelenbosch, M.P., Zivkovic, D. (2008) d-Asb11 is an essential mediator of canonical Delta-Notch signalling. Nat. Cell Biol. 10: 1190-1198.

Dormeyer, W., van Hoof, D., Braam, S.R., Heck, A.J.R., Mummery, C.L., Krijgsveld, J. (2008) Plasma membrane proteomics of human embryonic stem cells and human embryonal carcinoma cells. J. Proteome Res. 7: 2936-2951.

Dormeyer, W., van Hoof, D., Mummery, C.L., Krijgsveld, J., Heck, A.J. (2008) A practical guide for the identification of membrane and plasma membrane proteins in human embryonic stem cells and human embryonal carcinoma cells. Proteomics 8: 4036-4053.

el Azzouzi, H.E., de Windt, L.J. (2008) Heart spotting. Basic Res. Cardiol. 103: 228-231.

Faucherre, A., Taylor, G.S., Overvoorde, J., Dixon, J.E., den Hertog, J. (2008) Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic development. Oncogene 27: 1079-1086.

Feitsma, H.M. (2008) DNA mismatch repair, genome instability and cancer in zebrafish. Thesis, Univ. Utrecht, pp. 1-142.

Feitsma, H., Akay, A., Cuppen, E. (2008) Alkylation damage causes MMR-dependent chromosomal instability in vertebrate embryos. Nucleic Acids Res. 36: 4047-4056.

Feitsma, H., Cuppen, E. (2008) Zebrafish as a cancer model. Mol. Cancer Res. 6: 685-694.

Feitsma, H., de Bruijn, E., van de Belt, J., Nijman, I.J., Cuppen, E. (2008) Mismatch repair deficiency does not enhance ENU mutagenesis in the zebrafish germ line. Mutagenesis 23: 325-329.

Feitsma, H., Kuiper, R.V., Korving, J., Nijman, I.J., Cuppen, E. (2008) Zebrafish with mutations in mismatch repair genes develop neurofibromas and other tumors. Cancer Res. 68: 5059-5066.

Ferdinandusse, S., Zomer, A.W.M., Komen, J.C., van den Brink, C.E., Thanos, M., Hamers, F.P.T., Wanders, R.J.A., van der Saag, P.T., Poll-The, B.T., Brites, P. (2008) Ataxia with loss of Purkinje cells in a mouse model for Refsum disease. Proc. Natl. Acad. Sci. 105: 17712-17717.

Freund, C., Ward-van Oostwaard, D., Monshouwer-Kloots, J., van den Brink, S., van Rooijen, M., Xu, X., Zweigerdt, R., Mummery, C., Passier, R. (2008) Insulin redirects differentiation from cardiogenic mesoderm and endoderm to neuroectoderm in differentiating human embryonic stem cells. Stem Cells 26: 724-733.

Goessling, W., North, T.E., Lord, A.M., Ceol, C., Lee, S., Weidinger, G., Bourque, C., Strijbosch, R., Haramis, A.P., Puder, M., Clevers, H., Moon, R.T., Zon, L.I. (2008) APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development. Dev. Biol. 320: 161-174.

Gort, E.H., van Haaften, G., Verlaan, I., Groot, A.J., Plasterk, R.H.A., Shvarts, A., Suijkerbuijk, K.P.M., van Laar, T., van der Wall, E., Raman, V., van Diest, P.J., Tijsterman, M., Vooijs, M. (2008) The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2α. Oncogene 27: 1501-1510.

Goumans, M.J., Carvalho, R., Mummery, C., ten Dijke, P. (2008) The TGF-β family in endothelial cell differentiation and cardiovascular development and function. In: The TGF-β family. Eds. Derynck, R., Miyazono, K., Cold Spring Harbor Laboratory Press, Cold Spring Harbor, pp. 761-788.

Graichen, R., Xu, X., Braam, S.R., Balakrishnan, T., Norfiza, S., Sieh, S., Soo, S.Y., Tham, S.C., Mummery, C., Colman, A., Zweigerdt, R., Davidson, B.P. (2008) Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK. Differentiation 76: 357-370.

Groen, A., Overvoorde, J., van der Wijk, T., den Hertog, J. (2008) Redox regulation of dimerization of the receptor protein-tyrosine phosphatases RPTPα, LAR, RPTPμ and CD45. FEBS J. 275: 2597-2604.

Guryev, V., Saar, K., Adamovic, T., Verheul, M., van Heesch, S.A.A.C., Cook, S., Pravenec, M., Aitman, T., Jacob, H., Shull, J.D., Hubner, N., Cuppen, E. (2008) Distribution and functional impact of DNA copy number variation in the rat. Nat. Genet. 40: 538-545.

Hatzis, P., van der Flier, L.G., van Driel, M.A., Guryev, V., Nielsen, F., Denissov, S., Nijman, I.J., Koster, J., Santo, E.E., Welboren, W., Versteeg, R., Cuppen, E., van de Wetering, M., Clevers, H., Stunnenberg, H.G. (2008) Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells. Mol. Cell. Biol. 28: 2732-2744.

Herpers, R., van de Kamp, E., Duckers, H.J., Schulte-Merker, S. (2008) Redundant roles for Sox7 and Sox18 in arteriovenous specification in zebrafish. Circ. Res. 102: 12-15.

Hogan, B.M., Bussmann, J., Wolburg, H., Schulte-Merker, S. (2008) ccm1 cell autonomously regulates endothelial cellular morphogenesis and vascular tubulogenesis in zebrafish. Hum. Mol. Genet. 17: 2424-2432.

Holstege, J.C., de Graaff, W., Hossaini, M., Cardona Cano, S., Jaarsma, D., van den Akker, E., Deschamps, J. (2008) Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice. Proc. Natl. Acad. Sci. 105: 6338-6343.

Homberg, J.R., de Boer, S.F., Raaso, H.S., Olivier, J.D.A., Verheul, M., Ronken, E., Cools, A.R., Ellenbroek, B.A., Schoffelmeer, A.N.M., Vanderschuren, L.J.M.J., de Vries, T.J., Cuppen, E. (2008) Adaptations in pre- and postsynaptic 5-HT1A receptor function and cocaine supersensitivity in serotonin transporter knockout rats. Psychopharmacology 200: 367-380.

Homberg, J.R., van den Bos, R., den Heijer, E., Suer, R., Cuppen, E. (2008) Serotonin transporter dosage modulates long-term decision-making in rat and human. Neuropharmacology 55: 80-84.

Houwing, S. (2009) Piwi-RNA complexes in the zebrafish germline. Thesis, Univ. Utrecht, pp. 1-134.

Houwing, S., Berezikov, E., Ketting, R.F. (2008) Zili is required for germ cell differentiation and meiosis in zebrafish. EMBO J. 27: 2702-2711.

Jaks, V., Barker, N., Kasper, M., van Es, J.H., Snippert, H.J., Clevers, H., Toftgard, R. (2008) Lgr5 marks cycling, yet long-lived, hair follicle stem cells. Nat. Genet. 40: 1291-1299.

Jansen, M. (2008) Gastrointestinal polyposis syndromes: clinical and molecular aspects with an emphasis on Peutz-Jeghers syndrome. Thesis, Univ. Utrecht, pp. 1-104.

Joziasse, I.C., van de Smagt, J.J., Smith, K., Bakkers, J., Sieswerda, G.J., Mulder, B.J.M., Doevendans, P.A. (2008) Genes in congenital heart disease: atrioventricular valve formation. Basic Res. Cardiol. 103: 216-227.

Karatas, A., Hegner, B., de Windt, J.L., Luft, F.C., Schubert, C., Gross, V., Akashi, Y.J., Gurgen, D., Kintscher, U., de Costa Goncalves, A.C., Regitz-Zagrosek, V., Dragun, D. (2008) Deoxycorticosterone acetate-salt mice exhibit blood pressure-independent sexual dimorphism. Hypertension 51; 1177-1183.

Kedrin, D., Gligorijevic, B., Wyckoff, J., Verkhusha, V.V., Condeelis, J., Segall, J.E., van Rheenen, J. (2008) Intravital imaging of metastatic behavior through a mammary imaging window. Nat. Methods 5: 1019-1021.

Koudijs, M.J., den Broeder, M.J., Groot, E., van Eeden, F.J.M. (2008) Genetic analysis of two zebrafish patched homologues identifies novel roles for the hedgehog signaling pathway. BMC Dev. Biol. 8: 15.

Krens, S.F.G., He, S., Lamers, G.E.M., Meijer, A.H., Bakkers, J., Schmidt, T., Spaink, H.P., Snaar-Jagalska, B.E. (2008) Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation. Dev. Biol. 319: 370-383.

Krijgsveld, J., Whetton, A.D., Lee, B., Lemischka, I., Oh, S., Pera, M., Mummery, C., Heck, A.J.R. (2008) Proteome biology of stem cells: a new joint HUPO and ISSCR initiative. Mol. Cell. Proteomics 7: 204-205.

Kruisselbrink, E., Guryev, V., Brouwer, K., Pontier, D.B., Cuppen, E., Tijsterman, M. (2008) Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans. Curr. Biol. 18: 900-905.

Leal, M.C., Feitsma, H., Cuppen, E., Franca, L.R., Schulz, R.W. (2008) Completion of meiosis in male zebrafish (Danio rerio) despite lack of DNA mismatch repair gene mlh1. Cell Tissue Res. 332: 133-139.

Lebrin, F., Mummery, C.L. (2008) Endoglin-mediated vascular remodeling: mechanisms underlying hereditary hemorrhagic telangiectasia. Trends Cardiovasc. Med. 18: 25-32.

Lemeer, S.M. (2008) Mapping protein phosphorylation in zebrafish development. Thesis, Univ. Utrecht, pp. 1-142.

Lemeer, S., Jopling, C., Gouw, J., Mohammed, S., Heck, A.J.R., Slijper, M., den Hertog, J. (2008) Comparative phosphoproteomics of zebrafish Fyn/Yes morpholino knockdown embryos. Mol. Cell. Proteomics 7:2176-2187.

Lemeer, S., Pinkse, M.W.H., Mohammed, S., van Breukelen, B., den Hertog, J., Slijper, M., Heck, A.J.R. (2008) Online automated in vivo zebrafish phosphoproteomics: from large-scale analysis down to a single embryo. J Proteome Res. 7: 1555-1564.

Linsen, S.E.V., Tops, B.B.J., Cuppen, E. (2008) miRNAs: small changes, widespread effects. Cell Research 18: 1157-1159.

Mokry, M., Cuppen, E. (2008) The Atp1a1 gene from inbred Dahl salt sensitive rats does not contain the A1079T missense transversion. Hypertension 51: 922-927.

Monteiro, R., Chuva de Sousa Lopes, S.M., Bialecka, M., de Boer, S., Zwijsen, A., Mummery, C.L. (2008) Real time monitoring of BMP Smads transcriptional activity during mouse development. Genesis 46: 335-346.

Monteiro, R., van Dinther, M., Bakkers, J., Wilkinson, R., Patient, R., ten Dijke, P., Mummery, C. (2008) Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish. Dev. Biol. 315: 55-71.

Nijman, I.J., Kuipers, S., Verheul, M., Guryev, V., Cuppen, E. (2008) A genome-wide SNP panel for mapping and association studies in the rat. BMC Genomics 9: 95.

Nijman, I.J., van Boxtel, D.C.J., van Cann, L.M., Marnoch, Y., Cuppen, E., Lenstra, J.A. (2008) Phylogeny of Y chromosomes from bovine species. Cladistics 24: 723-726.

Offerhaus, G.J.A., Milne, A.N.A., Oving, I.M., van Gijn, M.E., Hruban, R.H., Clevers, H. (2008) A transgenic mouse model for “lipid hang-up”, or why pathologists need to be involved in genetically engineered mouse modelling. Gut 57: 1739-1740.

Olivier, J.D.A., Cools, A.R., Olivier, B., Homberg, J.R., Cuppen, E., Ellenbroek, B.A. (2008) Stress-induced hyperthermia and basal body temperature are mediated by different 5-HT1A receptor populations: a study in SERT knockout rats. Eur. J. Pharmacol. 500: 190-197.

Olivier, J.D.A., van der Hart, M.G.C., van Swelm, R.P.L., Dederen, P.J., Homberg, J.R., Cremers, T., Deen, P.M.T., Cuppen, E., Cools, A.R., Ellenbroek, B.A. (2008) A study in male and female 5-HT transporter knockout rats: an animal model for anxiety and depression disorders. Neuroscience 152: 573-584.

Passier, R., van Laake, L.W., Mummery, C.L. (2008) Stem-cell-based therapy and lessons from the heart. Nature 453: 322-329.

Postel, R. (2008) Identification and characterization of novel genes by reverse and forward genetics in zebrafish. Thesis, Univ. Utrecht, pp. 1-120.

Postel, R., Vakeel, P., Topczewski, J., Knoll, R., Bakkers, J. (2008) Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex. Dev. Biol. 318: 92-101.

Riccio, O., van Gijn, M.E., Bezdek, A.C., Pellegrinet, L., van Es, J.H., Zimber-Strobl, U., Strobl, L.J., Honjo, T., Clevers, H., Radtke, F. (2008) Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2. EMBO Rep. 9: 377-383.

Rodriguez, F., Vacaru, A., Overvoorde, J., den Hertog, J. (2008) The receptor protein-tyrosine phosphatase, Dep1, acts in arterial/venous cell fate decisions in zebrafish development. Dev. Biol. 324: 122-130.

Saar, K., Beck, A., Bihoreau, M.T., Birney, E., Brocklebank, D., Chen, Y., Cuppen, E., Demonchy, S., Dopazo, J., Flicek, P., Foglio, M., Fujiyama, A., Gut, I.G., Gauguier, D., Guigo, R., Guryev, V., Heinig, M., Hummel, O., Jahn, N., Klages, S., Kren, V., Kube, M., Kuhl, H., Kuramoto, T., Kuroki, Y., Lechner, D., Lee, Y.A., Lopez-Bigas, N., Lathrop, G.M., Mashimo, T., Medina, I., Mott, R., Patone, G., Perrier-Cornet, J.A., Platzer, M., Pravenec, M., Reinhardt, R., Sakaki, Y., Schilhabel, M., Schulz, H., Serikawa, T., Shikhagaie, M., Tatsumoto, S., Taudien, S., Toyoda, A., Voigt, B., Zelenika, D., Zimdahl, H., Hubner, N. The STAR Consortium (2008) SNP and haplotype mapping for genetic analysis in the rat. Nat Genet. 40: 560-566.

Smith, K.A., Chocron, S., von der Hardt, S., de Pater, E., Soufan, A., Bussmann, J., Schulte-Merker, S., Hammerschmidt, M., Bakkers, J. (2008) Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells. Dev. Cell 14: 287-297.

Sotoca, A.M., Ratman, D., van der Saag, P., Strom, A., Gustafsson, J.A., Vervoort, J., Rietjens, I.M.C.M., Murk, A.J. (2008) Phytoestrogen-mediated inhibition of the human T47D breast cancer cells depends on the ERα/ERβ ratio. J. Steroid Biochem. Mol. Biol. 112: 171-178.

Sotoca Covaleda, A.M., van den Berg, H., Vervoort, J., van der Saag, P., Strom, A., Gustafsson, J.A., Rietjens, I., Murk, A.J. (2008) Influence of cellular ERα/ERβ ratio on the ERα-agonist induced proliferation of human T47D breast cancer cells. Toxicol. Sci. 105: 303-311.

Spoorendonk, K.M., Peterson-Maduro, J., Renn, J., Trowe, T., Kranenbarg, S., Winkler, C., Schulte-Merker, S. (2008) Retinoic acid and Cyp26b1 are critical regulators of osteogenesis in the axial skeleton. Development 135: 3765-3774.

Takada, S., Yamashita, Y., Berezikov, E., Hatanaka, H., Fujiwara, S.I., Kurashina, K., Watanabe, H., Enomoto, M., Soda, M., Choi, Y.L., Mano, H. (2008) MicroRNA expression profiles of human leukemias. Leukemia 22: 1274-1278.

ter Veld, M.G.R., Zawadzka, E., van den Berg, J.H.J., van der Saag, P.T., Rietjens, I.M.C.M., Murk, A.J. (2008) Food-associated estrogenic compounds induce estrogen receptor-mediated luciferase gene expression in transgenic male mice. Chem. Biol. Interact. 174: 126-133.

Thomas, N.A., Koudijs, M., van Eeden, F.J.M., Joyner, A.L., Yelon, D. (2008) Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential. Development 135: 3789-3799.

Tyler, D.M., Okamura, K., Chung, W.J., Hagen, J.W., Berezikov, E., Hannon, G.J., Lai, E.C. (2008) Functionally distinct regulatory RNAs generated by bidirectional transcription and processing of microRNA loci. Genes Dev. 22: 26-36.

van Boxtel, R., Toonen, P.W., van Roekel, H.S., Verheul, M., Smits, B.M.G., Korving, J., de Bruin, A., Cuppen, E. (2008) Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis. Carcinogenesis 29: 1290-1297.

van Boxtel, R., Toonen, P.W., Verheul, M., van Roekel, H.S., Nijman, I.J., Guryev, V., Cuppen, E. (2008) Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals. BMC Genomics 9: 460.

van den Akker, W.M.R., Brox, A., Puelles, L., Durston, A.J., Medina, L. (2008) Comparative functional analysis provides evidence for a crucial role for the homeobox gene Nkx2.1/Titf-1 in forebrain evolution. J. Comp. Neurol. 506: 211-223.

van Ham, T.J., Thijssen, K.L., Breitling, R., Hofstra, R.M.W., Plasterk, R.H.A., Nollen, E.A.A. (2008) C. elegans model identifies genetic modifiers of α-synuclein inclusion formation during aging. PLoS Genet. 4: 1000027.

van Hoof, D., Braam, S.R., Dormeyer, W., Ward-van Oostwaard, D., Heck, A.J.R., Krijgsveld, J., Mummery, C.L. (2008) Feeder-free monolayer cultures of human embryonic stem cells express an epithelial plasma membrane protein profile. Stem Cells 26: 2777-2781.

van Laake, L.W. (2008) Cardiac recovery by stem and progenitor cells. Thesis, Univ. Utrecht, pp. 1-248.

van Laake, L.W., Passier, R., Doevendans, P.A., Mummery, C.L. (2008) Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents. Circ. Res. 102: 1008-1010.

van Rooijen, E. (2008) Genetic analysis of the ciliary protein Lrrc50 and the von Hippel-Lindau tumor suppressor in zebrafish. Thesis, Univ. Utrecht, pp. 1-178.

van Rooijen, E., Giles, R.H., Voest, E.E., van Rooijen, C., Schulte-Merker, S., van Eeden, F.J. (2008) LRRC50, a conserved ciliary protein implicated in polycystic kidney disease. J. Am. Soc. Nephrol. 19: 1128-1138.

van Stralen, E. (2008) The role of transcription factor MAFB in multiple myeloma. Thesis, Univ. Utrecht, pp. 1-148.

Weiss, H., Arndt, T., Jorns, A., Lenzen, S., Cuppen, E., Hedrich, H.J., Tiedge, M., Wedekind, D. (2008) The mutation of the LEW.1AR1-iddm rat maps to the telomeric end of rat chromosome 1. Mamm. Genome 19: 292-297.

Whetton, A.D., Williamson, A.J.K., Krijgsveld, J., Lee, B.H., Lemischka, I., Oh, S., Pera, M., Mummery, C., Heck, A.J.R. (2008) The time is right: proteome biology of stem cells. Cell Stem Cell 2: 215-217.

Wu, S.M., Chien, K.R., Mummery, C. (2008) Origins and fates of cardiovascular progenitor cells. Cell 132: 537-543.

Xu, X.Q., Graichen, R., Soo, S.Y., Balakrishnan, T., Bte Rahmat, S.N., Sieh, S., Tham, S.C., Freund, C., Moore, J., Mummery, C., Colman, A., Zweigerdt, R., Davidson, B.P.  (2008) Chemically defined medium supporting cardiomyocyte differentiation of human embryonic stem cells. Differentiation 76: 958-970.

Yang, P.T. (2008) Wnt secretion and signaling in Caenorhabditis elegans. Thesis, Univ. Utrecht, pp. 1-154.

Yang, P.T., Lorenowicz, M.J., Silhankova, M., Coudreuse, D.Y., Betist, M.C., Korswagen, H.C. (2008). Wnt signaling requires retromer-dependent recycling of MIG-14/Wntless in Wnt-producing cells. Dev. Cell 14: 140-147.

2007
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Feitsma, H., Leal, M.C., Moens, P.B., Cuppen, E., Schulz, R.W. (2007) Mlh1 deficiency in zebrafish results in male sterility and aneuploid as well as triploid progeny in females. Genetics 175: 1561-1569.

Fielitz, J., van Rooij, E., Spencer, J.A., Shelton, J.M., Latif, S., van der Nagel, R., Bezprozvannaya, S., de Windt, L., Richardson, J.A., Bassel-Duby, R., Olson, E.N. (2007) Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infartction. Proc. Natl. Acad. Sci 104: 4377-4382.

Filipczyk, A.A., Laslett, A.L., Mummery, C., Pera, M.F. (2007) Differentiation is coupled to changes in the cell cycle regulatory apparatus of human embryonic stem cells. Stem Cell Res. 1: 46-60.

Filipczyk, A.A., Passier, R., Rochat, A., Mummery, C.L. (2007) Regulation of cardiomyocyte differentiation of embryonic stem cells by extracellular signalling. Cell. Mol. Life Sci. 64: 704-718.

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Homberg, J.R., Schiepers, O.J.G., Schoffelmeer, A.N.M., Cuppen, E., Vanderschuren, L.J.M.J. (2007) Acute and constitutive increases in central serotonin levels reduce social play behaviour in peri-adolescent rats. Psychopharmacology 195: 175-182.

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Jopling, C., den Hertog, J. (2007) Essential role for Csk upstream of Fyn and Yes in zebrafish gastrulation. Mech. Dev. 124: 129-136.

Jopling, C., van Geemen, D., den Hertog, J. (2007) Shp2 knockdown and Noonan/LEOPARD mutant Shp2-induced gastrulation defects. PLoS Genet. 3: e225.

Kammenga, J.E., Doroszuk, A., Riksen, J.A.G., Hazendonk, E., Spiridon, L., Petrescu, A.J., Tijsterman, M., Plasterk, R.H.A., Bakker, J. (2007) A Caenorhabditis elegans wild type defies the temperature-size rule owing to a single nucleotide polymorphism in tra-3. PLoS Genet. 3: e34.

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Mummery, C. (2007) Cardiomyocytes from human embryonic stem cells: more than heart repair alone. Bioessays 29: 572-579.

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Wehkamp, J., Wang, G., Kubler, I., Nuding, S., Gregorieff, A., Schnabel, A., Kays, R.J., Fellermann, K., Burk, O., Schwab, M., Clevers, H., Bevins, C.L., Stange, E.F. (2007) The paneth cell alpha-defensin deficiency of ileal Crohn’s disease is linked to Wnt/Tcf-4. J. Immunol. 179: 3109-3118.

Windahl, S.H., Lagerquist, M.K., Andersson, N., Jochems, C., Kallkopf, A., Hakansson, C., Inzunza, J., Gustafsson, J.A., van der Saag, P.T., Carlsten, H., Pettersson, K., Ohlsson, C. (2007) Identification of target cells for the genomic effects of estrogens in bone. Endocrinology 148: 5688-5695.

Yang, J., Groen, A., Lemeer, S., Jans, A., Slijper, M., Roe, S.M., den Hertog, J., Barford, D. (2007) Reversible oxidation of the membrane distal domain of receptor PTPalpha is mediated by a cyclic sulfenamide. Biochemistry 46: 709-719.

2006
Ason, B., Darnell, D.K., Wittbrodt, B., Berezikov, E., Kloosterman, W.P., Wittbrodt, J., Antin, P.B., Plasterk, R.H.A. (2006) Differences in vertebrate microRNA expression. Proc. Natl. Acad. Sci. 103: 14385-14389.

Barker, N., Clevers, H. (2006) Mining the Wnt pathway for cancer therapeutics. Nat. Rev. Drug Discov. 5: 997-1014.

Beqqali, A., Kloots, J., Ward-van Oostwaard, D., Mummery, C., Passier, R. (2006) Genome-wide transcriptional profiling of human embryonic stem cells differentiating to cardiomyocytes. Stem Cells 24: 1956-1967.

Berezikov, E., Cuppen, E., Plasterk, R.H.A. (2006) Approaches to microRNA discovery. Nat. Genet. 38: S2-S7.

Berezikov, E., Thuemmler, F., van Laake, L.W., Kondova, I., Bontrop, R., Cuppen, E., Plasterk, R.H.A. (2006) Diversity of microRNAs in human and chimpanzee brain. Nat. Genet. 38: 1375-1377.

Berezikov, E., van Tetering, G., Verheul, M., van de Belt, J., van Laake, L., Vos, J., Verloop, R., van de Wetering, M., Guryev, V., Takada, S., van Zonneveld, A.J., Mano, H., Plasterk, R., Cuppen, E. (2006) Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis. Genome Res. 16: 1289-1298.

Bijlsma, M.F., Spek, C.A., Zivkovic, D., van de Water, S., Rezaee, F., Peppelenbosch, M.P. (2006) Repression of smoothened by patched-dependent (pro-)vitamin D3 secretion. PLoS Biol. 4: e232.

Chuva de Sousa Lopes, S.M., Hassink, R.J., Feijen, A., van Rooijen, M.A., Doevendans, P.A., Tertoolen, L., Brutel de la Riviere, A., Mummery, C.L. (2006) Patterning the heart, a template for human cardiomyocyte development. Dev. Dyn. 235: 1994-2002.

Chuva de Sousa Lopes, S.M., Mummery, C.L. (2006) Differentiation in early development. In: Essentials of Stem Cell Biology. Ed. Lanza, R., San Diego, Elsevier Academic Press, pp. 101-110.

Chuva de Sousa Lopes, S.M., Mummery, C.L., Thorsteinsdottir, S. (2006) Implantation and placentation. In: Cell signaling and growth factors in development: from molecules to organogenesis. Eds. Unsicker, K., Krieglstein, K., Weinheim, Wiley Verlag GmbH & Co., pp. 73-105.

Clevers, H. (2006) Colon cancer - understanding how NSAIDs work. N. Engl. J. Med. 354: 761-763.

Clevers, H. (2006) Wnt/ß-catenin signaling in development and disease. Cell 127: 469-480.

Clevers, H., Batlle, E. (2006) EphB/EphrinB receptors and Wnt signaling in colorectal cancer. Cancer Res. 66: 2-5.

Coudreuse, D.Y.M., Roel, G., Betist, M.C., Destree, O., Korswagen, H.C. (2006) Wnt gradient formation requires retromer function in Wnt-producing cells. Science 312: 921-924.

Creyghton, M.P., Roel, G., Eichhorn, P.J.A., Vredeveld, L.C., Destree, O., Bernards, R. (2006) PR130 is a modulator of the Wnt-signaling cascade that counters repression of the antagonist Naked cuticle. Proc. Natl. Acad. Sci. 103: 5397-5402.

Cvetanovic, M., Mitchell, J.E., Patel, V., Avner, B.S., Su, Y., van der Saag, P.T., Witte, P.L., Fiore, S., Levine, J.S., Ucker, D.S. (2006) Specific recognition of apoptotic cells reveals a ubiquitous and unconventional innate immunity. J. Biol. Chem. 281: 20055-20067.

de Boer, T.P., Kok, B., Roel, G., van Veen, T.A.B., Destree, O.H.J., Rook, M.B., Vos, M.A., de Bakker, J.M.T., van der Heyden, M.A.G. (2006) Cloning, embryonic expression, and functional characterization of two novel connexins from Xenopus laevis. Biochem. Biophys. Res. Commun. 349: 855-862.

de Jonge, N., Goumans, M.J., Lips, D., Hassink, R., Vlug, E.J., van der Meel, R., Emmerson, C.D., Nijman, J., de Windt, L., Doevendans, P.A. (2006) Controlling cardiomyocyte survival. In: Novartis Found. Symp. 274, pp. 41-51.

Diks, S.H., Bink, R.J., van de Water, S., Joore, J., van Rooijen, C., Verbeek, F.J., den Hertog, J., Peppelenbosch, M.P., Zivkovic, D. (2006) The novel gene asb11: a regulator of the size of the neural progenitor compartment. J. Cell Biol. 174: 581-592.

Fitzgerald, K., Tertyshnikova, S., Moore, L., Bjerke, L., Burley, B., Cao, J., Carroll, P., Choy, R., Doberstein, S., Dubaquie, Y., Franke, Y., Kopczynski, J., Korswagen, H., Krystek Jr., S.R., Lodge, N.J., Plasterk, R., Starrett, J., Stouch, T., Thalody, G., Wayne, H., van der Linden, A., Zhang, Y., Walker, S.G., Cockett, M., Wardwell-Swanson, J., Ross-Macdonald, P., Kindt, R.M. (2006) Chemical genetics reveals an RGS/G-protein role in the action of a compound. PLoS Genet. 2: e57.

Fujimura, Y., Isono, K., Vidal, M., Endoh, M., Kajita, H., Mizutani-Koseki, Y., Takihara, Y., van Lohuizen, M., Otte, A., Jenuwein, T., Deschamps, J., Koseki, H. (2006) Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8. Development 133: 2371-2381.

Gazzoli, I. (2006) Genetic etiology of hereditary colorectal cancer: new mechanisms and advanced mutation detection techniques. Thesis, Univ. Utrecht, pp. 1-166.

Giles, R.H., Lolkema, M.P., Snijckers, C.M., Belderbos, M., van der Groep, P., Mans, D.A., van Beest, M., van Noort, M., Goldschmeding, R., van Diest, P.J., Clevers, H., Voest, E.E. (2006) Interplay between VHL/HIF1a and Wnt/ß-catenin pathways during colorectal tumorigenesis. Oncogene 25: 3065-3070.

Gregorieff, A. (2006) Wnt signaling in gut development and homeostatis. Thesis, Univ. Utrecht, pp. 1-114.

Griesel, G., Treichel, D., Collombat, P., Krull, J., Zembrzycki, A., van den Akker, W.M.R., Gruss, P., Simeone, A., Mansouri, A. (2006) Sp8 controls the anteroposterior patterning at the midbrain-hindbrain border. Development 133: 1779-1787.

Groen, A. (2006) Redox regulation of receptor protein-tyrosine phosphatases. Thesis, Univ. Utrecht, pp. 1-130.

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Haramis, A.-P.G., Hurlstone, A., van der Velden, Y., Begthel, H., van den Born, M., Offerhaus, G.J.A., Clevers, H.C. (2006) Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia. EMBO Rep. 7: 444-449.

Holstege, F.C.P., Clevers, H. (2006) Transcription factor target practice. Cell 124: 21-23.

Homberg, J., Mudde, J., Braam, B., Ellenbroek, B., Cuppen, E., Joles, J.A. (2006). Blood pressure in mutant rats lacking the 5-hydroxytryptamine transporter. Hypertension 48: e115-e116.

Huang, Z., Xie, H., Ioannidis, V., Held, W., Clevers, H., Sadim, M.S., Sun, Z. (2006) Transcriptional regulation of CD4 gene expressing by T cell factor-1/ß-catenin pathway. J. Immunol. 176: 4880-4887.

Jansen, M., de Leng, W.W.J., Baas, A.F., Myoshi, H., Mathus-Vliegen, L. , Taketo, M.M., Clevers, H., Giardiello, F.M., Offerhaus, G.J.A. (2006) Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis. Gut 55: 1-5.

Jopling, J.C. (2006) Gastrulation signalling makes the round go long. Thesis, Univ. Utrecht, pp. 1-114.

Ketting, R.F. (2006) Partners in dicing. Genome Biol. 7: 210.

Kloosterman, W.P., Plasterk, R.H.A. (2006) The diverse functions of microRNAs in animal development and disease. Dev. Cell 11: 441-450.

Kloosterman, W.P., Steiner, F.A., Berezikov, E., de Bruijn, E., van de Belt, J., Verheul, M., Cuppen, E., Plasterk, R.H.A. (2006) Cloning and expression of new microRNAs from zebrafish. Nucleic Acids Res. 34: 2558-2569.

Kloosterman, W.P., Wienholds, E., de Bruijn, E., Kauppinen, S., Plasterk, R.H.A. (2006) In situ detection of miRNAs in animal embryos using LNA-modified oligonucleotide probes. Nat. Methods 3: 27-29.

Korswagen, H.C. (2006) Regulation of the Wnt/ß-catenin pathway by redox signaling. Dev. Cell 10: 687-688.

Kuchler, A.M., Gjini, E., Peterson-Maduro, J., Cancilla, B., Wolburg, H., Schulte-Merker, S. (2006) Development of the zebrafish lymphatic system requires VEGFC signaling. Curr. Biol. 16: 1244-1248.

Kuiper, G.G.J.M., Klootwijk, W., Morvan Dubois, G., Destree, O., Darras, V.M., Van der Geyten, S., Demeneix, B., Visser, T.J. (2006) Characterization of recombinant Xenopus laevis type I iodothyronine deiodinase: substitution of a proline residue in the catalytic center by serine (Pro132Ser) restores sensitivity to 6-propyl-2-thiouracil. Endocrinology 147: 3519-3529.

Li, Y., Alvarez, O.A., Gutteling, E.W., Tijsterman, M., Fu, J., Riksen, J.A.G., Hazendonk, E., Prins, P., Plasterk, R.H.A., Jansen, R.C., Breitling, R., Kammenga, J.E. (2006) Mapping determinants of gene expressing plasticity by genetical genomics in C. elegans. PLoS Genet. 2: 2155-2161.

Malliri, A., Rygiel, T.P., van der Kammen, R.A., Song, J.Y., Engers, R., Hurlstone, A.F.L., Clevers, H., Collard, J.G. (2006) The Rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development. J. Biol. Chem. 281: 543-548.

Markiewicz, E., Tilgner, K., Barker, N., van de Wetering, M., Clevers, H., Dorobek, M., Hausmanowa-Petrusewicz, I., Ramaekers, F.C.S., Broers, J.L.V., Blankesteijn, W.M., Salpingidou, G., Wilson, R.G., Ellis, J.A., Hutchison, C.J. (2006) The inner nuclear membrane protein Emerin regulates ß-catenin activity by restricting its accumulation in the nucleus. Embo J. 25: 3275-3285.

Mitola, S., Brenchio, B., Piccinini, M., Tertoolen, L., Zammataro, L., Breier, G., Rinaudo, M.T., den Hertog, J., Arese, M., Bussolino, F. (2006) Type I collagen limits VEGFR-2 signaling by a SHP2 protein-tyrosine phosphatase-dependent mechanism 1. Circ. Res. 98: 45-54.

Moore, J.C., de Boer, T.P., van der Heyden, M.A.G., Tertoolen, L.G.J., Mummery, C.L. (2006) Stem cells and cardiomyocytes. In: Cardiovascular research: new technologies, methods, and applications. Eds. Pasterkamp, G., de Kleijn, D.P.V., New York, Springer Science, pp. 133-155.

Muncan, V., Sansom, O.J., Tertoolen, L., Phesse, T.J., Begthel, H., Sancho, E., Cole, A.M., Gregorieff, A., Moreno de Alboran, I., Clevers, H., Clarke, A.R. (2006) Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc. Mol. Cell. Biol. 26: 8418-8426.

Nelson, P.T., Baldwin, D.A., Kloosterman, W.P., Kauppinen, S., Plasterk, R.H.A., Mourelatos, Z. (2006) RAKE and LNA-ISH reveal microRNA expression and localization in archival human brain. RNA 12: 187-191.

Passier, R., Denning, C., Mummery, C. (2006) Cardiomyocytes from human embryonic stem cells. In: Handb. Exp. Pharmacol. 174. Eds. Starke, K., Born, G., Duckles, S., Eichelbaum, M., Ganten, D., Hofmann, F., Rosenthal, W., Rubany, G., Berlin, Springer-Verlag, pp. 101-122.

Peres, J.N., Durston, A.J. (2006) Role of X-Delta-2 in the early neural development of Xenopus laevis. Dev. Dyn. 235: 802-810.

Peres, J.N., McNulty, C.L., Durston, A.J. (2006) Interaction between X-Delta-2 and Hox genes regulates segmentation and patterning of the anteroposterior axis. Mech. Dev. 123: 321-333.

Plasterk, R.H.A. (2006) microRNAs in animal development. Cell 124: 877-881.

Quaedackers, M.E. (2006) Inhibition of NF-?B transcriptional activity by the estrogen receptor: insights into the molecular mechanism. Thesis, Univ. Utrecht, pp. 1-130.

Radtke, F., Clevers, H., Riccio, O. (2006) From gut homeostasis to cancer. Curr. Mol. Med. 6: 275-289.

Sanna, B., Brandt, E.B., Kaiser, R.A., Pfluger, P., Witt, S.A., Kimball, T.R., van Rooij, E., de Windt, L.J., Rothenberg, M.E., Tschop, M.H., Benoit, S.C., Molkentin, J.D. (2006) Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo. Proc. Natl. Acad. Sci. 103: 7327-7332.

Smits, B.M.G., Cuppen, E. (2006) Rat genetics: the next episode. Trends Genet. 22: 232-240.

Smits, B.M.G., Cuppen, E. (2006) Rats go genomic. Genome Biol. 7: 306.

Smits, B.M.G., Mudde, J.B., van de Belt, J., Verheul, M., Olivier, J., Homberg, J., Guryev, V., Cools, A.R., Ellenbroek, B.A., Plasterk, R.H.A., Cuppen, E. (2006) Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis. Pharmacogenet. Genomics 16: 159-169.

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Steiner, F.A., Plasterk, R.H.A. (2006) Knocking out the Argonautes. Cell 127: 667-668.

Stern, C.D., Charite, J., Deschamps, J., Duboule, D., Durston, A.J., Kmita, M., Nicolas, J.F., Palmeirim, I., Smith, J.C., Wolpert, L. (2006) Head-tail patterning of the vertebrate embryo: one, two or many unresolved problems? Int. J. Dev. Biol. 50: 3-15.

Takada, S., Berezikov, E., Yamashita, Y., Lagos-Quintana, M., Kloosterman, W.P., Enomoto, M., Hatanaka, H., Fujiwara, S., Watanabe, H., Soda, M., Choi, Y.L., Plasterk, R.H.A., Cuppen, E., Mano, H. (2006) Mouse microRNA profiles determined with a new and sensitive cloning method. Nucleic Acids Res. 34: e115.

Taniguchi, Y., Takeda, S., Furutani-Seiki, M., Kamei, Y., Todo, T., Sasado, T., Deguchi, T., Kondoh, H., Mudde, J., Yamazoe, M., Hidaka, M., Mitani, H., Toyoda, A., Sakaki, Y., Plasterk, R.H.A., Cuppen, E. (2006) Generation of medaka gene knockout models by target-selected mutagenesis. Genome Biol. 7: R116.

ter Veld, M.G.R., Schouten, B., Louisse, J., van Es, D.A., van der Saag, P.T., Rietjens, I.M.C.M., Murk, A.J. (2006) Estrogenic potency of food-packaging-associated plasticizers and antioxidants as detected in ERa and ERß reporter gene cell lines. J. Agric. Food Chem. 54: 4407-4416.

Thiele, A., Nagamine, Y., Hauschildt, S., Clevers, H. (2006) AU-rich elements and alternative splicing in the ß-catenin 3’UTR can influence the human ß-catenin mRNA stability. Exp. Cell Res. 312: 2367-2378.

Thijssen, V.L.J.L., Postel, R., Brandwijk, R.J.M.G.E., Dings, R.P.M., Nesmelova, I., Satijn, S., Verhofstad, N., Nakabeppu, Y., Baum, L.G., Bakkers, J., Mayo, K.H., Poirier, F., Griffioen, A.W. (2006) Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy. Proc. Natl. Acad. Sci. 103: 15975-15980.

Tops, B.B.J., Plasterk, R.H.A., Ketting, R.F. (2006) The Caenorhabditis elegans Argonautes ALG-1 and ALG-2; almost identical yet different. In: Cold Spring Harbor Symposia on Quantitative Biology, symposium 71, pp. 189-194.

van den Broek, O. (2006) TCF1 during early embryogenesis. Thesis, Univ. Utrecht, pp. 1-110.

van der Meer, D.L.M., Marques, I.J., Leito, J.T.D., Besser, J., Bakkers, J., Schoonheere, E., Bagowski, C.P. (2006) Zebrafish cypher is important for somite formation and heart development. Dev. Biol. 299: 356-372.

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van Hoof, D., Passier, R., Ward-van Oostwaard, D., Pinkse, M.W.H., Heck, A.J.R., Mummery, C.L., Krijgsveld, J. (2006) A quest for human and mouse embryonic stem cell-specific proteins. Mol. Cell. Proteomics 5: 1261-1273.

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van Nes, J. (2006) Function of Caudal related homeobox (Cdx) genes in mouse embryonic and extra-embryonic development. Thesis, Univ. Utrecht, pp. 1-138.

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