Hubrecht publications

1981-1990

1990
Beddington, R.S.P. and Lawson, K.A. Clonal analysis of cell lineages. In: Postimplantation Mammalian Embryos, a Practical Approach, edited by Copp, A.J. and Cockroft, D.L. Oxford: IRL Press, 1990, p. 267-292. The Practical Approach Series.

Bierman, A.J., Koenderman, L., Tool, A.J. and De Laat, S.W. Epidermal growth factor and bombesin differ strikingly in the induction of early responses in Swiss 3T3 cells. J.Cell.Physiol. 142:441-448, 1990.

Boterenbrood, E.C. and Narraway, J.M. Epiboly connected with cleavage in morula and early blastula stages of Xenopus laevis, a study using time-lapse photography. W.Roux'Arch.Dev.Biol. 198:303-307, 1990.

De Graaf, A., Van Hemert, F.J., Linnemans, W.A.M., Brakenhoff, G.J., De Jong, L., Van Renswoude, A.J.B. and Van Driel, R. Three-dimensional distribution of DNase I-sensitive chromatin regions in interphase nuclei of embryonal carcinoma cells. Eur.J.Cell Biol. 52:135-141, 1990.

De Groot, R.P. and Kruijer, W. Transcriptional activation by TGFb1 mediated by the dyad symmetry element (DSE) and the TPA responsive element (TRE). Biochem.Biophys.Res.Comm. 168:1074-1081, 1990.

De Groot, R.P., Rijken, P.J., Den Hertog, J., Boonstra, J., Verkleij, A.J., De Laat, S.W. and Kruijer, W. Microgravity decreases c-fos induction and serum response element activity. J.Cell Sci. 97:33-38, 1990.

De Groot, R.P., Kruyt, F.A.E., Van Der Saag, P.T. and Kruijer, W. Ectopic expression of c-jun leads to differentiation of P19 embryonal carcinoma cells. EMBO J. 9:1831-1837, 1990.

De Groot, R.P., Schoorlemmer, J.A., Van Genesen, S.T. and Kruijer, W. Differential expression of jun and fos genes during differentiation of mouse P19 embryonal carcinoma cells. Nucl.Acids Res. 18:3195-3202, 1990.

De Groot, R.P., Rijken, P.J., Den Hertog, J., Boonstra, J., Verkleij, A.J., De Laat, S.W. and Kruijer, W. Epidermal growth factor induced signal transduction in A431 cells is influenced by altered gravity conditions. In: Proceedings of the Fourth Eur.Symp.on Life Sciences Research in Space, edited by David, V. Paris: ESA, 1990, p. 243-248. Trieste, Italy, May-June 1990. ESA SP-307.

De Loos, F.A.M. Morphology of the bovine oocyte in relation to its maturation. Thesis, Univ. Utrecht, pp. 1-110, 1990.

Kastrop, P.M.M., Bevers, M.M., Destrée, O.H.J. and Kruip, T.A.M. Analysis of protein synthesis in morphologically classified bovine follicular oocytes before and after maturation in vitro. Mol.Reprod.Dev. 26:222-226, 1990.

Kastrop, P.M.M., Bevers, M.M., Destrée, O.H.J. and Kruip, T.A.M. Changes in protein synthesis and phosphorylation patterns during bovine oocyte maturation in vitro. J.Reprod.Fertil. 90:305-310, 1990.

Kastrop, P.M.M. Bovine oocyte maturation; biochemical aspects. Thesis, Univ. Utrecht, pp. 1-114, 1990.  

Kress, C., Vogels, R., De Graaff, W.G.A.J., Bonnerot, C., Meijlink, F., Nicolas, J.F. and Deschamps, J.T. Hox-2.3 upstream sequences mediate lacZ expression in intermediate mesoderm derivatives of transgenic mice. Development 109:775-786, 1990.

Meijlink, F. and Hulspas, M. Groei wordt steeds beter begrepen. Intermediair 26:39-41, 1990.

Mummery, C.L., Slager, H.G., Kruijer, W., Feijen, A., Freund, E.C.A., Koornneef, I. and Van Den Eijnden-Van Raaij, A.J.M. Expression of transforming growth factor b2 during the differentiation of murine embryonal carcinoma and embryonic stem cells. Dev.Biol. 137:161-170, 1990.

Mummery, C.L., Feijen, A., Freund, E.C.A. and Shen, S. Characteristics of embryonic stem cell differentiation: a comparison with two embryonal carcinoma cell lines. Cell Diff.Dev. 30:195-206, 1990.

Mummery, C.L. and Van Den Eijnden-Van Raaij, A.J.M. Growth factors and their receptors in differentiation and early murine development. Cell Diff.Dev. 30:1-18, 1990.

Mummery, C.L., Van Den Eijnden-Van Raaij, A.J.M., Feijen, A., Freund, E.C.A., Hulskotte, E.G.J., Schoorlemmer, J.A. and Kruijer, W. Expression of growth factors during the differentiation of embryonic stem cells in monolayer. Dev.Biol. 142:406-413, 1990.

Nieuwkoop, P.D. and Albers, B. The role of competence in the cranio-caudal segregation of the central nervous system. Dev. Growth Diff. 32:23-31, 1990.

Otte, A.P., Kramer, IJ.M., Mannesse, M., Lambrechts, A.C. and Durston, A.J. Characterization of protein kinase C in early Xenopus embryogenesis. Development 110:461-470, 1990.

Otte, A.P. Molecular mechanisms of neural induction and competence in Xenopus laevis. Thesis, Univ. Utrecht, pp. 1-78, 1990.

Otte, A.P., Roy, D., Siemerink, M., Koster, C.H., Hochstenbach, F., Timmermans, J.P.M. and Durston, A.J. Characterization of a maternal type VI collagen in Xenopus embryos suggests a role for collagen in gastrulation. J.Cell Biol. 111:271-278, 1990.

Otte, A.P., Bruinooge, E., Van Driel, R., De Vente, J. and Durston, A.J. Cyclic GMP is not involved in neural induction in Xenopus laevis. Roux's Arch.Dev.Biol. 199:97-101, 1990.

Rijken, P.J., De Groot, R.P., Kruijer, W., Boonstra, J., Verkleij, A.J. and De Laat, S.W. Epidermal growth factor (EGF)-induced signal transduction in A431 cells is sensitive to gravity. In: Microgravity as a Tool in Developmental Biology, edited by Guyenne, T.D. Paris: ESA, 1990, p. 21-28. Proc. Special ESA Symp. Held during the 11th Intern. Congr. of ISDB, Utrecht, August 1989. ESA Publ. SP-1123.

Schilthuis, J.G. Regulation of expression of histone genes during early development of Xenopus laevis. Thesis, Univ. Utrecht, pp. 1-104, 1990.

Slootweg, M.C., Van Buul-Offers, S.C., Hoogerbrugge, C.M., Herrmann-Erlee, M.P.M., Van Den Eijnden-Van Raaij, A.J.M., Duursma, S.A. and Van Zoelen, E.J.J. Characterization of growth factor activity produced by fetal mouse osteoblasts. J.Endocrinol. 124:301-309, 1990.

Slootweg, M.C., Van Genesen, S.T., Otte, A.P., Duursma, S.A. and Kruijer, W. Activation of mouse osteoblast growth hormone receptor: c-fos oncogene expression independent of phosphoinositide breakdown and cyclic AMP. J.of Mol.Endocrinol. 4:265-274, 1990.

Snoek, G.T., Koster, C.H., De Laat, S.W., Heideveld, M., Durston, A.J. and Van Zoelen, E.J.J. Effects of cell heterogeneity on production of polypeptide growth factors and mesoderm-inducing activity by Xenopus laevis XTC cells. Exp.Cell Res. 187:203-210, 1990.

Spaargaren, M., Defize, L.H.K., De Laat, S.W. and Boonstra, J. Antibody-induced activation of the epidermal growth factor receptor tyrosine kinase requires the presence of detergent. Biochem.Biophys.Res.Comm. 171:882-889, 1990.

Tilly, B.C., Tertoolen, L.G.J., Remorie, R., Ladoux, A., Verlaan, I., De Laat, S.W. and Moolenaar, W.H. Histamine as a growth factor and chemoattractant for human carcinoma and melanoma cells: action through Ca2+-mobilizing H1 receptors. J.Cell Biol. 110:1211-1215, 1990.

Tilly, B.C., Tertoolen, L.G.J., Lambrechts, A.C., Remorie, R., De Laat, S.W. and Moolenaar, W.H. Histamine-H1-receptor-mediated phosphoinositide hydrolysis. Ca2+ signalling and membrane-potential oscillations in human Hela carcinoma cells. Biochem.J. 266:235-243, 1990.

Tilly, B.C., Lambrechts, A.C., Tertoolen, L.G.J., De Laat, S.W. and Moolenaar, W.H. Regulation of phosphoinositide hydrolysis induced by histamine and guanine nucleotides in human Hela carcinoma cells; calcium and pH dependence and inhibitory role of protein kinase C. FEBS letters 265:80-84, 1990.

Tsung, H.-C. and Mummery, C.L. Effects of feeder layer and BRL conditioned medium on mouse embryonic stem cells. Cell Research 1:35-51, 1990.

Ubbels, G.A., Berendsen, W., Kerkvliet, S.C.J. and Narraway, J.M. The first seven minutes of a Xenopus egg fertilised on a sounding rocket in space. In: Microgravity as a Tool in Developmental Biology, edited by Guyenne, T.D. Paris: ESA, 1990, p. 49-58. 

Ubbels, G.A. and Willemsen, H.P. Automatic experiment container for fertilisation of frog eggs in space - a multi-purpose piece of classified space hardware. In: Microgravity as a Tool in Developmental Biology, edited by Guyenne, T.D. Paris: ESA , 1990, p. 75-78.

Ubbels, G.A., Berendsen, W., Kerkvliet, S.C.J. and Narraway, J.M. Fertilization of Xenopus eggs in Space. In: Proceedings of the Fourth Eur.Symp. on Life Sciences Research in Space, edited by David, V. Paris: ESA, 1990, p. 249-254.

Ubbels, G.A., Kerkvliet, S.C.J., Narraway, J.M. and Berendsen, W. Fertilization of frog eggs in space. In: TEXUS 17-20 Abschlussbericht, edited by Ahlborn, H. Bonn: Deutsche Agentur f.Raumfahrtangelegenheiten, 1990, p. 48-54.

Van Belzen, N. Interaction of epidermal growth factor (EGF) receptors with the cytoskeleton. Thesis, Univ. Utrecht, pp. 1-92, 1990.

Van Belzen, N., Spaargaren, M., Verkleij, A.J. and Boonstra, J. Interaction of epidermal growth factor receptors with the cytoskeleton is related to receptor clustering. J.Cell.Physiol. 145:365-375, 1990.

Van Den Eijnden-Van Raaij, A.J.M., Koornneef, I., Slager, H.G., Mummery, C.L. and Van Zoelen, E.J.J. Characterization of polyclonal anti-peptide antibodies specific for transforming growth factor b2. J.Immunol.Methods 133:107-118, 1990.

Van Den Eijnden-Van Raaij, A.J.M., Van Zoelen, E.J.J., Van Nimmen, K., Koster, C.H., Snoek, G.T., Durston, A.J. and Huylebroeck, D. Activin-like factor from a Xenopus laevis cell line responsible for mesoderm induction. Nature 345:732-734, 1990.

Van Der Burg, B., De Groot, R.P., Isbrücker, L., Kruijer, W. and De Laat, S.W. Stimulation of TPA-responsive element activity by a cooperative action of insulin and estrogen in human breast cancer cells. Mol.Endocrinol. 4:1720-1726, 1990.

Van Der Burg, B., Isbrücker, L., Van Selm-Miltenburg, A.J.P., De Laat, S.W. and Van Zoelen, E.J.J. Role of estrogen-induced insulin-like growth factors in the proliferation of human breast cancer cells. Cancer Res. 50:7770-7774, 1990.

Van Der Burg, B. Molecular action of steroids and growth factors in breast tumor cells. Thesis, Univ. Utrecht, pp. 1-106, 1990.

Van Erp, H.E., Rijksen, G, Van Der Saag, P.T. and Staal, G.E.J. Phosphofructokinase and pyruvate kinase in mouse embryonal carcinoma P19 cells in relation to growth and differentiation. Differentiation 45:199-205, 1990.

Vogels, R., De Graaff, W.G.A.J. and Deschamps, J.T. Expression of the murine homeobox-containing gene Hox-2.3 suggests multiple time-dependent and tissue specific roles during development. Development 110:1159-1168, 1990.

Wan Su, J., Tertoolen, L.G.J., De Laat, S.W., Hage, W.J. and Durston, A.J. Intercellular communication is cell cycle modulated during early Xenopus laevis development. J.Cell Biol. 110:115-121, 1990.

Weima, S.M., Van Rooijen M.A., Mummery, C.L., Feijen, A., De Laat, S.W. and Van Zoelen, E.J.J. Identification of the type-b receptor for platelet-derived growth factor in human embryonal carcinoma cells. Exp. Cell Res. 186:324-331, 1990

1989
Bluemink, J.G. (Ed.) From DNA to Bodyplan. Amsterdam: Elsevier, 1989, p. S1-S247. Abstracts 11th Intern. Congr. Int. Soc. Dev. Biol., Utrecht, August 1989. Cell Diff. Dev., 27 Suppl.

Boevé, M.H. and Van Zoelen, E.J.J. Heparin-binding growth factors in cannic vitreous. Med.Sci.Res. 17:295-296, 1989.

Boonstra, J., Van Belzen, N., Van Bergen en Henegouwen, P., Hage, W.J., Van Maurik, W.A.M., Wiegant, F.A.C. and Verkleij, A.J. The epidermal growth factor receptor. In: Immuno-Gold Labeling in Cell Biology, edited by Verkleij, A.J. and Leunissen, J.L.M. BocaRaton,Fl.: CRC Press, 1989, p. 259-276.

Boonstra, J., Defize, L.H.K., Van Bergen en Henegouwen, P., De Laat, S.W. and Verkleij, A.J. Characteristics of the epidermal growth factor receptor. In: Receptors, Membrane Transport and Signal Transduction, edited by Evangelopoulos, A.E., Changeux, J.P., Parker, L. et al.,  Berlin: Springer, 1989, p. 162-185. NATO ASI Series, Series H, 29.

Datson, N.A., Van Der Saag, P.T. and Oostra, B.A. RFLP for the human retinoic acid receptor gene RAR-b. Nucl.Acids Res. 17:8897, 1989.

De Laat, S.W., Bluemink, J.G. and Mummery, C.L. (Eds) Cell to Cell Signals in Mammalian Development, Berlin etc.:Springer-Verlag, 1989, p. 1-322. Proc. NATO Adv. Res. Workshop, Les Arcs, France, February 1988; NATO ASI Series, Series H: Cell Biology, 26.

De Loos, F.A.M., Van Vliet, C., Van Maurik, W.A.M. and Kruip, T.A.M. Morphology of immature bovine oocytes. Gamete Res. 24:197-204, 1989.

Defize, L.H.K., Boonstra, J., Van Bergen en Henegouwen, P., Verkleij, A.J. and De Laat, S.W. Activation of the human epidermal growth factor receptor. In: Cell to Cell Signal in Mammalian Development, edited by De Laat, S.W., Bluemink, J.G. and Mummery, C.L. Berlin: Springer, 1989, p. 163-181. Proc. NATO Adv. Res. Workshop, Les Arcs, France, February 1988; NATO ASI Series, Series H: Cell Biology, 26.

Defize, L.H.K., Boonstra, J., Meisenhelder, J., Kruijer, W., Tertoolen, L.G.J., Tilly, B.C., Hunter, T., Van Bergen en Henegouwen, P., Moolenaar, W.H. and De Laat, S.W. Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors. J.Cell Biol. 109:2495-2507, 1989.

Durston, A.J., Timmermans, J.P.M., Hage, W.J., Hendriks, H.F.J., De Vries, N.J., Heideveld, M. and Nieuwkoop, P.D. Retinoic acid causes an anteroposterior transformation in the developing central nervous system. Nature 340:140-144, 1989.

Fentener-Van Vlissingen, J.M., Van Zoelen, E.J.J., Ursem, P.J.F. and Wensing, C.G.J. In vitro model of the first phase of testicular descent: identification of a low molecular weight factor from fetal testis involved in proliferation of gubernaculum testis cells and distinct from specified polypeptide growth factors and fetal gonadal hormones. Endocrinology 123:2868-2877, 1989.

Kruys, V., Marinx, O., Shaw, G., Deschamps, J.T. and Huez, G. Translational blockade imposed by cytokinic-derived UA-rich sequences. Science 245:852-855, 1989.

Ludérus, M.E.E., Van Der Most, R.G., Otte, A.P. and Van Driel, R. A protein kinase C-related enzyme activity in Dictyostelium discoideum. FEBS Lett. 253:71-75, 1989.

1988
Meijlink, F., De Laaf, R.T.M., Verrijzer, P., De Graaff, W.G.A.J. and Deschamps, J.T. Regulation of expression of the Hox 2.3 gene. In: Cell to Cell Signals in Mammalian Development, edited by De Laat, S.W., Bluemink, J.G. and Mummery, C.L. Berlin: Springer, 1989, p. 23-41. Proc. NATO Adv. Res. Workshop, Les Arcs, France, 1988; NATO ASI Series, Series H: Cell Biology, 26.

Moolenaar, W.H. Signal transduction by growth factor receptors. In: Cell to Cell Signals in Mammalian Development, edited by De Laat, S.W., Bluemink, J.G. and Mummery, C.L. Berlin: Springer, 1989, p. 209-217. Proc. NATO Adv. Res. Workshop, Les Arcs, France, 1988; NATO ASI Series, Series H: Cell Biology, 26.

Mummery, C.L., Van Den Eijnden-Van Raaij, A.J.M., Feijen, A., Tsung, H.-C. and Kruijer, W. Regulation of growth factors and their receptors in early murine embryogenesis. In: Cell to Cell Signals in Mammalian Development, edited by De Laat, S.W., Bluemink, J.G. and Mummery, C.L. Berlin: Springer, 1989, p. 231-245. Proc. NATO Adv. Res. Workshop, Les Arcs, France, 1988; NATO ASI Series, Series H: Cell Biology, 26.

Noordermeer, J., Meijlink, F., Verrijzer, P., Rijsewijk, F. and Destrée, O.H.J. Isolation of the Xenopus homolog of int-1 wingless and expression during neurula stages of early development. Nucl.Acids Res. 17:11-18, 1989.

Otte, A.P., Van Run, R., Heideveld, M., Van Driel, R. and Durston, A.J. Neural induction is mediated by cross-talk between the protein kinase C and cyclic AMP pathways. Cell 58:641-648, 1989.

Piersma, A.H., Willemse, A., Van Den Brink, C.E., De Laat, S.W. and Mummery, C.L. Mesodermal differentiation of embryonal carcinoma cells in coculture with visceral endoderm cell lines. In: Cell to Cell Signals in Mammalian Development, edited by De Laat, S.W., Bluemink, J.G. and Mummery, C.L. Berlin: Springer, 1989, p. 247-260. Proc. NATO Adv. Res. Workshop, Les Arcs, France, 1988; NATO ASI Series, Series H: Cell Biology, 26.

Tilly, B.C. and Moolenaar, W.H. Inositol lipids in growth factor action. In: Inositol Lipids in Cell Signalling, edited by Michell, R.H., Drummond, A.R. and Downes, C.P. N.Y.: Acad.Press, 1989, p. 485-499.

Ubbels, G.A., Berendsen, W. and Narraway, J.M. Fertilization of frog eggs on a sounding rocket in space. In: Life Sciences and Space Research XXIII (5);Gravitational Biology, edited by Oser, H., Horneck, G., Cogoli, A., Ubbels, G.A., Wetzig, J. and Mergenhagen, D. Oxford: Pergamon, 1989, p. 187-197. Proc. Topical Meeting COSPAR Interdisc. Scient. Comm. F. and Proc. Workshops XVII and XVIII COSPAR 27th Plenary Meeting, Espoo, Finland, July 1988; Adv. Space Res. 9.

Ubbels, G.A. Developmental biology in space: why and how? In: Life Sciences and Space Research XXIII (5); Gravitational Biology, edited by Oser, H., Horneck, G., Cogoli, A., Ubbels, G.A., Wetzig, J. and Mergenhagen, D. Oxford: Pergamon, 1989, p. 131-134. Proc. Topical Meeting COSPAR Interdisc. Scient. Comm. F and Proc. Workshops XVII and XVIII COSPAR 27th Plenary Meeting, Espoo, Finland, July 1988;Adv. Space Res. 9.

Vaessen, R.T.M.J., Kootwijk, E., Mummery, C.L., Hilkens, J., Bootsma, D. and Van Kessel, A.G. Preferential expression of cellular retinoic acid binding protein in a subpopulation of neural cells in the developing mouse embryo. Differentiation 40:99-105, 1989.

Van 't Hof, R.J., Defize, L.H.K., Nuijdens, R., De Brabander, M., Verkleij, A.J. and Boonstra, J. Dynamics of epidermal growth factor receptor internalization studied by Nanovid light microscopy and electron microscopy in combination with immunogold labeling. Eur.J.Cell Biol. 48:5-13, 1989.

Van Bergen en Henegouwen, P., Defize, L.H.K., De Kroon, J., Van Damme, H., Verkleij, A.J. and Boonstra, J. Ligand-induced association of epidermal growth factor receptor to the cytoskeleton of A431 cells. J.Cell.Biochem. 39:455-465, 1989.

Van Den Eijnden-Van Raaij, A.J.M., Koornneef, I., Van Oostwaard, F.M.J., Feijen, A., Kruijer, W., De Laat, S.W. and Van Zoelen, E.J.J. Purification of a growth factor related to platelet-derived growth factor and a type b transforming growth factor secreted by mouse neuroblastoma cells; a general strategy for the purification of basic polypeptide growth factors. Biochem.J. 257:375-382, 1989.

Van Der Burg, B., Van Selm-Miltenburg, A.J.P., Van Maurik, W.A.M., Rutteman, G.R., Misdorp, W., De Laat, S.W. and Van Zoelen, E.J.J. Isolation of autonomously growing dog mammary tumor cell lines cultured in medium supplemented with serum treated to inactivate growth factors. J.Natl.Cancer Inst. 81:1545-1551, 1989.

Van Der Burg, B., Van Selm-Miltenburg, A.J.P., De Laat, S.W. and Van Zoelen, E.J.J. Direct effects of estrogen on c-fos and c-myc protooncogene expression and cellular proliferation in human breast cancer cells. Mol.Cell.Endocrinol. 64:223-228, 1989.

Van Der Saag, P.T. and Durston, A.J. De rol van retinylzuur in groei, differentiatie en ontwikkeling. Voeding 50:167-170, 1989. Papers 2de Symp. Vit. A Onderzoek in Nederland, Mijdrecht, 1989.

Van Zoelen, E.J.J., Ward-van Oostwaard, T.M.J., Nieuwland, R., Van Der Burg, B., Van Den Eijnden-Van Raaij, A.J.M., Mummery, C.L. and De Laat, S.W. Identification and characterization of polypeptide growth factors secreted by murine embryonal carcinoma cells. Dev.Biol. 133:272-283, 1989.

Van Zoelen, E.J.J. The role of polypeptide growth factors in phenotypic transformation of normal rat kidney cells. In: Cell to Cell Signals in Mammalian Development, edited by De Laat, S.W., Bluemink, J.G. and Mummery, C.L. Berlin: Springer, 1989, p. 271-288. NATO Adv. Res. Workshop, Les Arcs, France, 1988; NATO ASI Series, Series H: Cell Biology, 26.

Van Zoelen, E.J.J., Koornneef, I., Holthuis, J.C.M., Ward-van Oostwaard, T.M.J., Feijen, A., De Poorter, T.L., Mummery, C.L. and Van Buul-Offers, S.C. Production of insulin-like growth factors, platelet-derived growth factor, and transforming growth factors and their role in the density-dependent growth regulation of a differentiated embryonal carcinoma cell line. Endocrinology 124:2029-2041, 1989.

Van Zoelen, E.J.J. Receptor-ligand interaction: a new method for determining binding parameters without a priori assumptions on non-specific binding. Biochem.J. 262:549-556, 1989.

Verhoeff-de Fremery, R. Abnormalities occurring during early development of Ambystoma mexicanum and Xenopus laevis. Herpetopathologia 1:35-39, 1989.

Weima, S.M. Growth factors and growth factor receptors in human testicular teratocarcinoma. Thesis, Univ.Utrecht, pp. 1-100, 1989.

Weima, S.M., Stet, L.H., Van Rooijen, M.A., Van Buul-Offers, S.C., Van Zoelen, E.J.J., De Laat, S.W. and Mummery, C.L. Human teratocarcinoma cells express functional insulin-like growth factor I receptors. Exp.Cell Res. 184:427-439, 1989.

Weima, S.M., Van Rooijen, M.A., Feijen, A., Mummery, C.L., Van Zoelen, E.J.J., De Laat, S.W. and Van Den Eijnden-Van Raaij, A.J.M. Transforming growth factor-b and its receptor are differentally regulated in human embryonal carcinoma cells. Differentiation 413:245-253, 1989.

1988

Cell to Cell Signals in Mammalian Development, Utrecht:NIOB, 1988, pp. 1-52.

Abstracts NATO Adv. Res. Workshop; Les Arcs, France, February 1988.

Bangma, G.C. The Embryological Collection of the Hubrecht Laboratory. J. Soc. Pres. Nat. Hist. Coll. 4:14-15, 1988.

Bierman, A.J., Cragoe, E.J.,Jr., De Laat, S.W. and Moolenaar, W.H. Bicarbonate determines cytoplasmic pH and suppresses mitogen-induced alkalinization in fibroblastic cells. J.Biol.Chem. 263:15253-15256, 1988.

Bierman, A.J. Na+/H+ exchange in cell growth and differentiation. Thesis, Univ. Utrecht, pp. 1-98, 1988.

Boonstra, J., Tertoolen, L.G.J., Mummery, C.L. and De Laat, S.W. Regulation of intracellular pH during the G1/S-phase transition of the neuroblastoma cell cycle. Exp.Cell Res. 174:521-524, 1988.

Cardellini, P., Rasotto, M.B., Tertoolen, L.G.J. and Durston, A.J. Intercellular communication in the eight-cell stage of Xenopus laevis development: a study using dye coupling. Dev.Biol. 129:265-269, 1988.

De Graaf, A. and Van Hemert, F.J. The use of large-fragment DNA polumerase I improves the DNAse dependence of the in situ nick-translation procedure. Nucl.Acids Res. 16:1621, 1988.

Defize, L.H.K., Arndt-Jovin, D.J., Jovin, T.M., Boonstra, J., Meisenkelder, J., Hunter, T., De Hey, H.T. and De Laat, S.W. A431 cell variants lacking the blood group A antigen display increased high affinity epidermal growth factor-receptor number, protein-tyrosine kinase activity, and receptor turnover. J.Cell Biol. 107:939-949, 1988.

Defize, L.H.K. Activation of the human epidermal growth factor receptor. Thesis, Univ. Utrecht, pp. 1-118, 1988.

Koster, J.G., Destrée, O.H.J. and Westerhoff, H.V. Kinetics of histone gene expression during early development of Xenopus laevis. J.Theor.Biol. 135:139-167, 1988.

Moolenaar, W.H., Bierman, A.J. and De Laat, S.W. Effects of growth factors on Na+/H+ exchange. In: Na+/H+ Exchange, edited by Grinstein, S. Boca Raton, Fl.: CRC Press, 1988, p. 227-234.

Moolenaar, W.H., Bierman, A.J., Tilly, B.C., Verlaan, I., Defize, L.H.K., Honegger, A.M., Ullrich, A. and Schlessinger, J. A point mutation at the ATP-binding site of the EGF-receptor abolishes signal transduction. EMBO J. 7:707-710, 1988. 

Otte, A.P., Koster, C.H., Snoek, G.T. and Durston, A.J. Protein kinase C mediates neural induction in Xenopus laevis. Nature 334:618-620, 1988.

Slootweg, M.C. Growth Hormone, Growth Factors and Osteoblasts. Thesis, Univ. Utrecht, pp. 1-105, 1988.

Snoek, G.T., Feijen, A., Hage, W.J., Van Rotterdam, W. and De Laat, S.W. The role of hydrophobic interactions in the phospholipid-dependent activation of protein kinase C. Biochem.J. 255:629-637, 1988.

Tertoolen, L.G.J., Kempenaar, J., Boonstra, J., De Laat, S.W. and Ponec, M. Lateral mobility of plasma membrane lipids in normal and transformed keratinocytes. Biochem.Biophys.Res.Comm. 152:491-496, 1988.

Tilly, B.C., Van Paridon, P.A., Verlaan, I., De Laat, S.W. and Moolenaar, W.H. Epidermal growth factor-induced formation of inositol phosphates in human A431 cells, differences from the effect of bradykinin. Biochem.J. 252:857-863, 1988.

Tilly, B.C. Inositol lipids in cellular signal transduction by growth factors. Thesis, Univ. Utrecht, pp. 1-90, 1988.

Timmers, H.T.M., Van Zoelen, E.J.J., Bos, J.L. and Van Der Eb, A.J. Cells transformed by adenovirus type 12 but not by type 5 are dependent on insulin or insulin-like growth factor I for their proliferation. J.Biol.Chem. 263:1329-1335, 1988.

Ubbels, G.A. A first…fertilisation of frog eggs in space. Microgravity News 1:19-23, 1988.

Van Belzen, N., Van Hemert, F.J. and Destrée, O.H.J. Eukaryotic messenger RNA degradation (correspondence). BioEssays 8:44, 1988.

Van Belzen, N., Rijken, P.J., Hage, W.J., De Laat, S.W., Verkleij, A.J. and Boonstra, J. Direct visualization and quantitative analysis of epidermal growth factor-induced receptor clustering. J.Cell.Physiol. 134:413-420, 1988.

Van Den Eijnden-Van Raaij, A.J.M., Koornneef, I. and Van Zoelen, E.J.J. A new method for high yield purification of type beta transforming growth factor from human platelets. Biochem.Biophys.Res.Comm. 157:16-23, 1988.

Van Den Eijnden-Van Raaij, A.J.M., Van Maurik, W.A.M., Boonstra, J., Van Zoelen, E.J.J. and De Laat, S.W. Ultrastructural localization of platelet-derived growth factor and related factors in normal and transformed cells. Exp.Cell Res. 178:479-492, 1988.

Van Der Burg, B., De Laat, S.W. and Van Zoelen, E.J.J. Mitogenic stimulation of human breast cancer cells in a growth factor-defined medium: synergistic action of insulin and estrogens. In: Progress in Cancer Research and Therapy, edited by Bresciani, F., King, R.J.B., Lippman, M.E. and Raynaud, J.-P. N.Y.: Raven Press, 1988, p. 231-233. Proc. 31st Intern. Congr. Hormones and Cancer, Hamburg, Sept. 1987; Progress in Cancer Research and Therapy, 35.

Van Der Burg, B., Rutteman, G.R., Blankenstein, M.A., De Laat, S.W. and Van Zoelen, E.J.J. Mitogenic stimulation of human breast cancer cells in a growth factor-defined medium: synergistic action of insulin and estrogen. J.Cell.Physiol. 134:101-108, 1988.

Van Hemert, F.J., Van Dam, A.P., Jonk, L.J.C., Destrée, O.H.J. and Smeenk, R.J.T. Monoclonal autoantibodies recognizing histone variants. Immunol.Invest. 17:195-215, 1988.

Van Zoelen, E.J.J., Van Oostwaard, F.M.J. and De Laat, S.W. The role of polypeptide growth factors in phenotypic transformation of normal rat kidney cells. J.Biol.Chem. 263:64-68, 1988.

Verrijzer, P., De Graaff, W.G.A.J., Deschamps, J.T. and Meijlink, F. Nucleotide sequence of the Hox 2.3 gene region. Nucl.Acids Res. 16:2729, 1988.

Weima, S.M., Van Rooijen, M.A., Mummery, C.L., Feijen, A., Kruijer, W., De Laat, S.W. and Van Zoelen, E.J.J. Differentially regulated production of platelet-derived growth factor and of transforming growth factor beta by a human teratocarcinoma cell line. Differentiation 38:203-210, 1988.

1987
Aarts, R.J., Durston, A.J. and Konijn, T.M. Cytoplasmic pH at the onset of development in Dictyostelium. J. Cell Sci. 87:423-430, 1987.

Albers, B. Competence as the main factor determining the size of the neural plate. Dev. Growth Diff. 29:535-545, 1987.

Bierman, A.J., Tertoolen, L.G.J., De Laat, S.W. and Moolenaar, W.H. The Na+/H+ exchanges is constitutively activated in P19 embryonal carcinoma cells, but not in a differentiated derivative; responsiveness to growth factors and other stimuli. J.Biol.Chem. 262:9621-9628, 1987.

Boonstra, J., Van Maurik, W.A.M. and Verkleij, A.J. Immunogold labelling of cryosections and cryofractures. In: Cryotechniques in Biological Electron Microscopy, edited by Steinbrecht, R.A. and Zierold, K. Berlin: Springer, 1987, p. 216-230.

Boonstra, J., Mummery, C.L., Feijen, A., De Hoog, W.J., Van Der Saag, P.T. and De Laat, S.W. Epidermal growth factor receptor expression during morphological differentiation of pheochromocytoma cells, induced by nerve growth factor or dibutyryl cyclic AMP. J.Cell.Physiol. 131:409-417, 1987.

Chandebois, R. and Faber, J. From DNA transcription to visible structure: what the development of multicellular animals teaches us. Acta Biotheoret. 36:61-119, 1987.

De Groot, R.P. Signal transduction by growth factor receptors. In: Jaarverslag 1987-Stichting Ruimteonderzoek Nederland (SRON), 2 p., 1987.

De Laat, S.W. and Verkleij, A.J. Regulation of cell growth and differentiation by microgravity. In: Jaarverslag 1987-Stichting Ruimteonderzoek Nederland (SRON), 2 p., 1987.

Defize, L.H.K., Mummery, C.L., Moolenaar, W.H. and De Laat, S.W. Antireceptor antibodies in the study of EGF-receptor interaction. Cell Diff. 20:87-102, 1987.

Deschamps, J.T., De Laaf, R.T.M., Verrijzer, P., De Gouw, M., Destrée, O.H.J. and Meijlink, F. The mouse Hox 2.3 homeobox-containing gene: regulation in differentiating pluripotent stem cells and expression pattern in embryos. Differentiation 35:21-30, 1987.

Deschamps, J.T., De Laaf, R.T.M., Joosen, L., Meijlink, F. and Destrée, O.H.J. Abundant expression of homeobox genes in mouse embryonal carcinoma cells correlates with chemically induced differentiation. Proc.Natn.Acad.Scis. 84:1304-1308, 1987.

Faber, J. Holisme als noodzakelijke benaderingswijze in de Embryologie. In: Holisme en Reductionisme in de Empirische Wetenschappen; Biologie, Geneeskunde, Psychologie, Sociologie, Economie, edited by Kuipers, T. Meppel: Boom Uitg., 1987, p. 21-27. Kennis en Methode, Tijdschr. voor Wetenschapsfilosofie en Methodologie.

Gerhart, J.C. The epigenetic nature of vertebrate development: an interview of Pieter D. Nieuwkoop on the occasion of his 70th birthday. Development 101:653-657, 1987.

Ikenishi, K. Functional gametes derived from explants of single blastomeres containing the "germ plasm" in Xenopus laevis: a genetic marker study. Dev.Biol. 122:35-38, 1987.

Klima, M. and Bangma, G.C. Unpublished drawings of marsupial embryos from the Hill Collection and some problems of marsupial ontogeny. Z.f.Säugetierkunde 52:201-211, 1987.

Lawson, K.A. and Pedersen, R.A. Cell fate, morphogenetic movement and population kinetics of embryonic endoderm at the time of germ layer formation in the mouse. Development 101:627-652, 1987.

Meijlink, F., De Laaf, R.T.M., Verrijzer, P., Destrée, O.H.J., Kroezen, V., Hilkens, J. and Deschamps, J.T. A mouse homeobox containing gene on chromosome 11: sequence and tissue-specific expression. Nucl.Acids Res. 15:6773-6786, 1987.

Moolenaar, W.H., Defize, L.H.K., Tilly, B.C., Bierman, A.J. and De Laat, S.W. Mechanisms of signal transduction by growth factor receptors. In: Hormones and Cell Regulation, edited by Dumont, J.E. and Nunez, J. London: Libbey Eurotext, 1987, p. 145-152. Coll. INSERM, 153.

Moolenaar, W.H., Defize, L.H.K., Tilly, B.C., Bierman, A.J. and De Laat, S.W. Mechanisms of signal transduction by growth factor receptors. In: Membrane Receptors, Dynamics and Energetics, edited by Wirtz, K.W.A. N.Y.: Plenum, 1987, p. 59-66. Proc. NATO Adv. Study Inst. on Membrane Receptors, Dynamics and Energetics, Spetsai, Greece, August 1986; NATO ASI Series, Series A: Life Sciences, 133.

Mummery, C.L., Van Rooijen, M.A., Van Den Brink, C.E. and De Laat, S.W. Cell cycle analysis during retinoic acid induced differentiation of a human embryonal carcinoma derived cell line. Cell Diff. 20:153-160, 1987.

Mummery, C.L., Van Den Brink, C.E. and De Laat, S.W. Commitment to differentiation induced by retinoic acid in P19 embryonal carcinoma cells is cell cycle dependent. Dev.Biol. 121:10-19, 1987.

Rijken, P.J. Growth factor-receptor interaction and receptor redistribution. In: Jaarverslag 1987-Stichting Ruimteonderzoek Nederland (SRON), 1 p., 1987.

Snoek, G.T., Boonstra, J., Ponec, M. and De Laat, S.W. Phorbol ester binding and protein kinase C activity in normal and transformed human keratinocytes. Exp.Cell Res. 172:146-157, 1987.

Tertoolen, L.G.J., Tilly, B.C., Irvine, R.F. and Moolenaar, W.H. Electrophysiological responses to bradykinin and microinjected inositol polyphosphates in neuroblastoma cells; possible role of inositol 1,3,4-triphosphate in altering membrane potential. FEBS letters 214:365-369, 1987.

Tilly, B.C., Van Paridon, P.A., Verlaan, I., Wirtz, K.W.A., De Laat, S.W. and Moolenaar, W.H. Inositol phosphate metabolism in bradykinin-stimulated human A431 carcinoma cells; relationship to calcium signalling. Biochem.J. 244:129-135, 1987.

Tilly, B.C., Van Paridon, P.A., Verlaan, I., Wirtz, K.W.A., De Laat, S.W. and Moolenaar, W.H. Bradykinin-induced inositol phosphate metabolism in human A431 epidermoid carcinoma cells. In: Membrane Receptors, Dynamics and Energetics, edited by Wirtz, K.W.A. N.Y.: Plenum, 1987, p. 51-57. Proc. NATO Adv. Study Inst., Spetsai, Greece, August 1986; NATO ASI Series, Series A: Life Sciences, 133.

Tilly, B.C., De Laat, S.W. and Moolenaar, W.H. Signal transduction by growth factors. In: Inositol lipids in cellular signalling, edited by Michell, R.H. and Putney, J.W.,Jr. N.Y.: Cold Spring Harbor, 1987, p. 145-149. Proc. Conf. Banbury Center, April 1987; Current Communications in Molecular Biology.

Ubbels, G.A. The role of gravity in the establishment of the dorso/ventral axis in the Amphibian embryo. In: Proc.of the Norderney Symp.on Scientific Results of the German Spacelab Mission D1, edited by Sahm, P.R., Jansen, R. and Keller, M.H. Köln, Wissensch. Projektführung, 1987, p. 431-437. Norderney, Germany, August 1986.
Ubbels, G.A. The role of gravity in the establishment of the dorso/ventral axis in the amphibian embryo. In: Biorack on Spacelab D1, edited by Longdon, N. and David, V. Paris: ESA, 1987, p. 147-155.

Van Belzen, N., Van Hemert, F.J. and Destrée, O.H.J. Eukaryotic messenger RNA degradation. BioEssays 6:221-226, 1987.

Van Den Eijnden-Van Raaij, A.J.M., Koornneef, I., Van Oostwaard, F.M.J., De Laat, S.W. and Van Zoelen, E.J.J. Cation-exchange high-performance liquid chromatography separation of highly basic proteins using volatile acidic solvents. Anal.Biochem. 163:263-269, 1987.

Van Den Eijnden-Van Raaij, A.J.M., Feijen, A. and Snoek, G.T. EDTA-extractable proteins from calf lens fiber membranes are phosphorylated by Ca2+-phospholipid-dependent protein kinase. Exp.Eye Res. 45:215-225, 1987.

Van Der Eb, A.J., Vaessen, R.T.M.J., Timmers, H.T.M., Offringa, R., Jochemsen, A.G., Bos, J.L. and Van Zoelen, E.J.J. The influence of adenovirus transformation on cellular gene expression. In: Viral carcinogenesis, edited by Kjeldgaard, N.O. and Forchhammer, J. Copenhagen: Munksgaard, 1987, p. 177-195. Alfred Benzon Symp., 24.

Van Der Valk, J., Verlaan, I., De Laat, S.W. and Moolenaar, W.H. Expression of pp60v-src alters the ionic permeability of the plasma membrane in rat cells. J.Biol.Chem. 262:2431-2434, 1987.

Van Veggel, J.H., Van Oostwaard, F.M.J., De Laat, S.W. and Van Zoelen, E.J.J. PC13 embryonal carcinoma cells produce a heparin-binding growth factor. Exp.Cell Res. 169:280-286, 1987.

Van Zoelen, E.J.J. The role of polypeptide growth factors and oncogenes in embryonic development. In: Comparative Pathophysiology of Regulatory Peptides, edited by Rijnberk, A. and Wimersma Greidanus, T.B. Basel: Karger, 1987. Proc. Meeting on Regulatory Peptides and Diseases of Companion Animals, Utrecht, Sept. 1986; Frontiers of Hormone Res. 17.

Van Zoelen, E.J.J., Van Rooijen, M.A., Van Oostwaard, F.M.J. and De Laat, S.W. Production of transforming growth factors by simian sarcoma virus-transformed cells. Cancer Res. 47:1582-1587, 1987.

Verhoeff-de Fremery, R. and Griffin, J. Anurans (frogs and toads). In: The UFAW Handbook on the Care and Management of Laboratory Animals, edited by Poole, T.B. Harlow,U.K.: Langman Publ., 1987, p. 773-783.

Verhoeff-de Fremery, R., Griffin, J. and Macgregor, H.C. Urodeles (newts and salamanders). In: The UFAW Handbook on the Care and Management of Laboratory Animals, edited by Poole, T.B. Harlow,U.K.: Langman Publ., 1987, p. 759-772.

Vervoordeldonk, F.J.M. Bijzondere diersoorten, gebruik van Xenopus en Bombina orientalis in het Hubrecht Laboratorium. Biotechniek 26:69-73, 1987.

1986

Aerts, R.J., Durston, A.J. and Moolenaar, W.H. Cytoplasmic pH and glycolysis in the Dictyostelium discoideum cell cycle. FEBS letters 196:167-170, 1986.

Bangma, G.C. De embryologische collectie van het Hubrecht Laboratorium. Vakbl. Biol.66:455-458, 1986.

Bluemink, J.G., Hage, W.J. and Bilinski, S. An ultrastructural study of plasma membrane lipid assembly during blastoderm formation in Drosophila. In: Progress in Developmental Biology, part A, edited by Slavkin, H.C. New York: Liss, 1986, p. 345-348. Proc. 10thIntern. Congr. Intern. Soc. Dev. Biol., Los Angeles, August, 1985; Progr. Clin. Biol. Res. 217A.

Boterenbrood, E.C. and Narraway, J.M. The direction of cleavage waves and the regional variation in the duration of cleavage cycles on the dorsal side of the Xenopus laevis blastula. W.Roux'Arch.Dev.Biol. 195:484-488, 1986.

De Laat, S.W. The Hubrecht Laboratory. ISDB News March:8-9, 1986.

Defize, L.H.K., Moolenaar, W.H., Van Der Saag, P.T. and De Laat, S.W. Dissociation of cellular responses to epidermal growth factor using anti-receptor monoclonal antibodies. EMBO J. 5:1187-1192, 1986.

Defize, L.H.K. and De Laat, S.W. Structural and functional aspects of epidermal growth factor (EGF) and its receptor. In: Phosphoproteins in Neuronal Function, edited by Gispen, W.H. and Routtenberg, A. Amsterdam: Elsevier, 1986, p. 169-182. Proc. 2ndIntern. Workshop State Univ. Utrecht, September 1985; Progress in Brain Res., 69.

Faber, J. A brief history of ISDB (1911-1985). ISDB News March:3-7, 1986.

Faber, J. Holisme als noodzakelijke benaderingswijze in de embryologie. Vakbl. Biol. 66:241-243, 1986.

Lawson, K.A., Meneses, J.J. and Pedersen, R.A. Cell fate and cell lineage in the endoderm of the presomite mouse embryo, studied with an intracellular tracer. Dev.Biol. 115:325-339, 1986.

Moolenaar, W.H., Bierman, A.J., Defize, L.H.K., Tilly, B.C. and De Laat, S.W. Signal transduction by growth factor receptors. In: Cell Cycle and Oncogenes, edited by Tanner, W. and Gallwitz, D. Heidelberg: Springer, 1986, p. 145-156.

Moolenaar, W.H. Effects of growth factors on intracellular pH regulation. Ann.Rev.Physiol. 48:363-376, 1986.

Moolenaar, W.H., Defize, L.H.K., Tilly, B.C., Bierman, A.J. and De Laat, S.W. Transmembrane signalling by growth factors. In: Membrane Pathology, edited by Bianchi, G., Carafoli, E. and Scarpa, A. New York: Acad. Scis, 1986, p. 491-502. Proc. Conf. Biol. Membr. Pathol., Como, May 1986; Ann. N.Y. Acad. Scis, 488.

Moolenaar, W.H., Defize, L.H.K., Van Der Saag, P.T. and De Laat, S.W. The generation of ionic signals by growth factors. In: Na+-H+ Exchange, Intracellular pH, and Cell Function, edited by Aronson, P.S. and Boron, W.F. Orlando,USA: Acad.Press, 1986, p. 137-156. Current Topics in Membranes and Transport, 26.

Moolenaar, W.H., Defize, L.H.K. and De Laat, S.W. Ionic signalling by growth factor receptors. J.Exp.Biol. 124:359-373, 1986.

Moolenaar, W.H., Kruijer, W., Tilly, B.C., Verlaan, I., Bierman, A.J. and De Laat, S.W. Growth factor-like action of phosphatidic acid. Nature 323:171-173, 1986.

Moolenaar, W.H. Regulation of cytoplasmic pH by na+/H+ exchange. Trends in Biochem.Scis 11:141-143, 1986.

Moolenaar, W.H., Defize, L.H.K. and De Laat, S.W. Calcium in the action of growth factors. In: Calcium and the Cell, edited by Evered, D. and Whelan, J. Chichester: Wiley, 1986, p. 212-231. Proc. Symp. On Calcium and the Cell, London, October 1985; CIBA Found. Symp., 122.

Moolenaar, W.H., Aerts, R., Tertoolen, L.G.J. and De Laat, S.W. The epidermal growth factor-induced calcium signal in A431 cells. J.Biol.Chem. 261:279-284, 1986.

Moolenaar, W.H. Cytoplasmic pH and free Ca2+ in the action of growth factors. In: Oncogenes and Growth Control, edited by Kahn, P. and Graf, T. Berlin: Springer-Verlag, 1986, p. 170-176.

Mummery, C.L., Feijen, A., Moolenaar, W.H., Van Den Brink, C.E. and De Laat, S.W. Establishment of a differentiated mesodermal line from P19 EC cells expressing functional PDGF and EGF receptors. Exp. Cell Res. 165:229-242, 1986.

Poelmann, R.E., Van Zoelen, E.J.J. and Boonstra, J. Nobelprijs Geneeskunde; Groeifactoren. Natuur en Techniek 54:928-933, 1986.

Selwood, L. The marsupial blastocyst - a study of the blastocysts in the Hill Collection. Austr.J.Zool. 34:177-187, 1986.

Snoek, G.T., Mummery, C.L., Van Den Brink, C.E., Van Der Saag, P.T. and De Laat, S.W. Protein kinase C and phorbol ester receptor expression related to growth and differentiation of nullipotent and pluripotent embryonal carcinoma cells. Dev.Biol. 115:282-292, 1986.

Snoek, G.T. and De Laat, S.W. Biochemisch onderzoek toont aan: Protein kinase C is sleutelenzym bij tumorpromotie. Kanker 10:100-103, 1986.

Snoek, G.T., Rosenberg, J., De Laat, S.W. and Gitler, C. The interaction of protein kinase C and other specific cytoplasmic proteins with phospholipid bilayers. Biochim.Biophys.Acta 860:336-344, 1986.

Tamura, T., Simon, E., Niemann, H., Snoek, G.T. and Bauer, H. 9p140v-fms molecules expressed at the surface of cells transformed by the McDonough strain of feline sarcoma virus are phosphorylated in tyrosine and serine. Mol. Cell. Biol. 6:4745-4748, 1986.

Ubbels, G.A. and Vermeulen, J.W.A.H. Dynamics of intracellular structure and cell determination during early development. Acta Histochem. 32:11-19, 1986. Proc. 26th Symp. Gesellsch. Histochemie, Maastricht, Sept. 1984.

Van Zoelen, E.J.J., Van Oostwaard, F.M.J. and De Laat, S.W. Transforming growth factor-b and retinoic acid modulate phenotypic transformation of normal rat kidney cells induced by epidermal growth factor and platelet-derived growth factor. J.Biol.Chem. 261:5003-5009, 1986.

Van Zoelen, E.J.J., Van Oostwaard, F.M.J. and De Laat, S.W. PDGF-like growth factor induces EGF-potentiated phenotypic transformation of normal rat kidney cells in the absence of TGFb. Biochem.Biophys.Res.Comm. 141:1229-1235, 1986.

Wiegant, F.A.C., Blok, F.J., Defize, L.H.K., Linnemans, W.A.M., Verkleij, A.J. and Boonstra, J. Epidermal growth factor receptors associated to cytoskeletal elements of epidermoid carcinoma (A431) cells. J.Cell Biol. 103:87-94, 1986.

1985
Aerts, R., Durston, A.J. and Moolenaar, W.H. Cytoplasmic pH and the regulation of the Dictyostelium cell cycle. Cell 43:653-657, 1985.

Bilinski, S.M., Hage, W.J. and Bluemink, J.G. Gap junctions between the follicle cells and the oocyte during oogenesis in an insect, Tribolium destructor/Coleoptera. W.Roux'Arch.Dev.Biol. 194:296-300, 1985.

Boonstra, J., Van Der Saag, P.T., Feijen, A., Bisschop, A. and De Laat, S.W. Epidermal growth factor, but not nerve growth factor, stimulates tyrosine-specific protein-kinase activity in pheochromocytoma (PC12) plasma membranes. Biochemie 67:1177-1183, 1985.

Boonstra, J., Van Maurik, W.A.M., Defize, L.H.K., De Laat, S.W., Leunissen, J.L.M. and Verkleij, A.J. Visualization of epidermal growth factor receptor in cryosections of cultured A431 cells by immuno-gold labeling. Eur.J.Cell Biol. 36:209-216, 1985.

Boonstra, J., De Laat, S.W. and Ponec, M. Epidermal growth factor receptor expression related to differentiation capacity in normal and transformed keratinocytes. Exp.Cell Res. 161:421-433, 1985.

Boonstra, J., Van Belzen, N., Van Maurik, W.A.M., Hage, W.J., Blok, F.J., Wiegant, F.A.C. and Verkleij, A.J. Immunocytochemical demonstrations of cytoplasmic and cell-surface EGF receptors in A431 cells using cryo-ultramicrotomy, surface replication, freeze-etching and label fracture. J.Microscopy 140:119-129, 1985.

Boonstra, J., Mummery, C.L., Van Der Saag, P.T. and De Laat, S.W. Two receptor classes for epidermal growth factor on pheochromocytoma cells, distinguishable by temperature, lectins, and tumor promoters. J.Cell.Physiol. 123:347-352, 1985.

Boonstra, J., Mummery, C.L., Van Zoelen, E.J.J., Van Der Saag, P.T. and De Laat, S.W. Cation transport during the cell cycle of neuroblastoma cells. In: Water and Ions in Biological Systems, edited by Pullman, A., Vasilescu, V. and Packer, L. N.Y.: Plenum Publ., 1985, p. 313-323. Proc. 2nd Intern. Conf. on Water and Ions in Biological Systems, Bucharest, September 1982.

De Laat, S.W., Boonstra, J., Moolenaar, W.H. and Mummery, C.L. Growth factor action and ionic signal transduction: characterization and relation to receptor expression. In: Growth and Maturation Factors vol.3, edited by Guroff, G. New York: Wiley, 1985, p. 219-249.

De Laat, S.W., Moolenaar, W.H., Defize, L.H.K., Boonstra, J. and Van Der Saag, P.T. Ionic signal transduction in growth factor action. In: The Molecular Basis of Movement through Membranes, edited by Quinn, P.J. and Pasternak, C.A. London: Biochem Soc., 1985, p. 205-220. Proc. Symp. Biochem. Soc., London, December 1984.

De Laat, S.W., Moolenaar, W.H., Defize, L.H.K., Boonstra, J. and Van Der Saag, P.T. Signal transduction by polypeptide growth factor receptors. In: Hormones and Cell Regulation, edited by Dumont, J.E., Hamprecht, B. and Nunez, J. Amsterdam: Elsevier, 1985, p. 269-288. Proc. 9th INSERM Eur. Symp. Sainte Odile (France), September 1984.

Moolenaar, W.H. and De Laat, S.W. Ionic signal transduction by growth factors. In: Mechanisms of Receptor Regulation, edited by Poste, G. and Crooke, S.T. N.Y.: Plenum, 1985, p. 131-147. Proc. Symp. Philadelphia, 1984. Series: New Horizons in Therapeutics.

Mummery, C.L., Feijen, A., Van Der Saag, P.T., Van Den Brink, C.E. and De Laat, S.W. Clonal variants of differentiated P19 embryonal carcinoma cells exhibit epidermal growth factor receptor kinase activity. Dev.Biol. 109,2:402-410, 1985.

Mummery, C.L., Feijen, A., Moolenaar, W.H., Van Den Brink, C.E. and De Laat, S.W. Establishment of a differentiated mesodermal line from P19 EC cells expressing functional PDGF and EGF receptors. Exp.Cell Res. 165:229-242, 1985.

Nieuwkoop, P.D. Inductive interaction and determination; a new approach to an old problem. In: Molecular Determinants of Animal Form, edited by Edelman, G.M. New York: A.R. Liss, 1985, p. 59-71. Proc. UCLA Symp., Park City, Utah, USA, March/April 1985; UCLA Symp. on Molecular and Cellular Biology, N.S., 31.

Nieuwkoop, P.D. Inductive interactions in early amphibian development and their general nature. In: Early Amphibian Development, edited by Slack, J. Cambridge: Comp. Biol., 1985, p. 333-347. Proc. Symp. Brit. Soc. Dev. Biol., Glasgow, March 1985; J. Embryol. Exp. Morphol. 89, suppl.

Nieuwkoop, P.D., Johnen, A.G. and Albers, B. The Epigenetic Nature of Early Chordate Development; Inductive Interaction and Competence. Cambridge: Univ. Press, 1985, p. 1-373. Developmental and Cell Biology Series, 16.

Speksnijder, J.E., Dohmen, M.R., Tertoolen, L.G.J. and De Laat, S.W. Regional differences in the lateral mobility of plasma membrane lipids in a molluscan embryo. Dev.Biol. 110:207-216, 1985.

Speksnijder, J.E., Mulder, M.M., Dohmen, M.R., Hage, W.J. and Bluemink, J.G. Animal-vegetal polarity in the plasma membrane of a molluscan egg: a quantitative free-fracture study. Dev.Biol. 108:38-48, 1985.

Ubbels, G.A. and Brom, T.G. Role of gravity in determination of the dorso-ventral axis in the developing embryo of "Xenopus laevis". In: Scientific Goals of the German Spacelab Mission D1, edited by Sahm, P.R. and Jansen, R. Koln: W.P.F., 1985, p. 179-180.

Van Zoelen, E.J.J., Van Oostwaard, F.M.J., Van Der Saag, P.T. and De Laat, S.W. Phenotypic transformation of normal rat kidney cells in a growth-factor defined medium: induction by a neuroblastoma-derived transforming growth factor independently of the EGF receptor. J.Cell.Physiol. 123:151-160, 1985.

Van Zoelen, E.J.J., Van De Ven, W.J.M., Franssen, H.J., Van Oostwaard, F.M.J., Van Der Saag, P.T., Heldin, C.-J. and De Laat, S.W. Neuroblastoma cells express c-sis and produce a transforming growth factor antigenically related to the platelet-derived growth factor. Mol. Cell. Biol. 5: 2289-2297, 1985.

Weijer, C.J. Cell type regulation in Dictyostelium discoideum. Thesis, Univ. Utrecht, pp. 1-141, 1985.

Weijer, C.J. and Durston, A.J. Influence of cyclic AMP and hydrolysis products on cell type regulation in Dictyostelium discoideum. J.Embryol.Exp.Morph. 86:19-37, 1985.

1984
Bluemink, J.G., Faber, J. and Lawson, K.A. Basement membranes and epithelia. Nature 312:107, 1984. Appendix: Nature 313:272, 1985.

Boonstra, J., Schamhart, D.H.J., De Laat, S.W. and Van Wijk, R. Analysis of K+ and Na+ transport and intracellular contents during and after heat shock and their role in protein synthesis in rat hepatoma cells. Cancer Res. 44:955-960, 1984.

Boonstra, J., Mummery, C.L., Defize, L.H.K., De Laat, S.W., Leunissen, J.L.M. and Verkleij, A.J. Epidermal growth factor-receptor interaction in rat pheochromocytoma (PC12) and human epidermoid A431 cells: biochemical and ultrastructural studies. Cell Biol.Intern.Rep. 8:275, 1984.

Brom, T.G., Ubbels, G.A. and Willemsen, H.P. An automatic device for amphibian egg fertilization in Space: technical aspects and biological requirements. In: Proc.2nd Eur.Symp.on Life Scis Research in Space. Paris: ESA, 1984, p. 13-17. Porz Wahn, Germany, June 1984; ESA SP 212.

De Laat, S.W., Boonstra, J., Mummery, C.L., Van Der Saag, P.T. and Van Zoelen, E.J.J. Membrane fluidity in growth and differentiation; the neuroblastoma cell model. In: Physiology of Membrane Fluidity, vol. II, edited by Shinitzky, M. Boca Raton Fl.: CRC Press, 1984, p. 21-51.

Dictus, W.J.A.G., Van Zoelen, E.J.J., Tetteroo, P.A.T., Tertoolen, L.G.J., De Laat, S.W. and Bluemink, J.G. Lateral mobility of plasma membrane lipids in Xenopus eggs: regional differences related to animal/vegetal polarity become extreme upon fertilization. Dev.Biol. 101:201-211, 1984.

Durston, A.J. The cell cycle in Dictyostelium discoideum development. In: Oscillations in Physiological Systems: Dynamics and Control. London: Inst. Measurement and Control, 1984, p. 7-14. Papers Symp., Oxford, Sept. 1984.

Durston, A.J., Weijer, C.J., Jongkind, J.F., Verkerk, A., Timmermans, J.P.M. and Te Kulve, W. A flow fluorimetric analysis of the cell cycle during growth and differentiation in Dictyostelium discoideum. W.Roux'Arch.Dev.Biol. 194:18-24, 1984.

Gadenne, M., Van Zoelen, E.J.J., Tencer, R. and De Laat, S.W. Increased rate of capping of concanavalin a receptors during early Xenopus development is related to changes in protein and lipid mobility. Dev.Biol. 104:461-468, 1984.

McDonald, S.A. and Durston, A.J. The cell cycle and sorting behaviour in Dictyostelium discoideum. J.Cell Sci. 66:195-204, 1984.

Michael, P. Are the primordial germ cells (PGCs) in Urodela formed by the inductive action of the vegetative yolk mass? Dev.Biol. 103:109-116, 1984.

Moolenaar, W.H., Tertoolen, L.G.J. and De Laat, S.W. Phorbol ester and diacylglycerol mimic growth factors in raising cytoplasmic pH. Nature 312:371-374, 1984.

Moolenaar, W.H., Tertoolen, L.G.J. and De Laat, S.W. Growth factors immediately raise cytoplasmic free Ca2+ in human fibroblasts. J.Biol.Chem. 259:8066-8069, 1984.

Moolenaar, W.H., Joosen, L. and De Laat, S.W. Ionic signal transduction by growth factors. In: Pepticle Hormones, Biomembranes, and Cell Growth, edited by Bolis, L., Verna, R. and Frati, L. N.Y.: Plenum Press, 1984, p. 215-231. Proc. Intern. Symp., Rome, October 1983.

Moolenaar, W.H., Tertoolen, L.G.J. and De Laat, S.W. The regulation of cytoplasmic pH in human fibroblasts. J.Biol.Chem. 259:7563-7569, 1984.

Mummery, C.L., Van Den Brink, C.E., Van Der Saag, P.T. and De Laat, S.W. The cell cycle, cell death, and cell morphology during retinoic acid-induced differentiation of embryonal carcinoma cells. Dev.Biol. 104:297-307, 1984.

Mummery, C.L., Van Den Brink, C.E., Van Der Saag, P.T. and De Laat, S.W. A short-term screening test for teratogens using differentiating neuroblastoma cells in vitro. Teratology 29:271-279, 1984.

Speksnijder, J.E., Mulder, M.M., Hage, W.J., Dohmen, M.R. and Bluemink, J.G. Regional differences in the numerical particle distribution in the plasma membrane of a molluscan egg. Cell Biol.Intern.Rep. 8:191, 1984.

Speksnijder, J.E., Dohmen, M.R., Van Zoelen, E.J.J., Tertoolen, L.G.J., Bluemink, J.G. and De Laat, S.W. Lateral mobility of plasma membrane lipids in a molluscan egg: evidence for an animal/vegetal polarity. Cell Biol.Intern.Rep. 8:270, 1984.

Tetteroo, P.A.T., Bluemink, J.G., Dictus, W.J.A.G., Van Zoelen, E.J.J. and De Laat, S.W. Lateral mobility of plasma membrane lipids in dividing Xenopus eggs. Dev.Biol. 104:210-218, 1984.

Ubbels, G.A. and Brom, T.G. Cytoskeleton and gravity at work in the establishment of dorso-ventral polarity in the egg of Xenopus laevis. Adv. Space Res. 4:9-18, 1984. Proc. 25th Cospar Conf., Graz, Austria, 1984.

Ullman, S.L. Early differentiation of the testis in the native cat, Dasyurus viverrinus (Marsupialia). J.Anat. 138:675-688, 1984.

Van Den Hoef, M.H.F., Bluemink, J.G. and De Laat, S.W. Gap junctions and rhombic particle arrays in the freeze-fractured mouse oocyte-follicle cell complex. Eur.J.Cell Biol. 35:312-316, 1984.

Van Den Hoef, M.H.F., Dictus, W.J.A.G., Hage, W.J. and Bluemink, J.G. The ultrastructural organization of gap junctions between follicle cells and the oocyte in Xenopus laevis. Eur.J.Cell Biol. 33:242-247, 1984.

Van Zoelen, E.J.J., Twardzik, D.R., Van Oostwaard, F.M.J., Van Der Saag, P.T., De Laat, S.W. and Todaro, G.J. Neuroblastoma cells produce transforming growth factors during exponential growth in a defined hormone-free medium. Proc.Natn.Acad.Scis. 81:4085-4089, 1984.

Verhoeff-de Fremery, R. Survey of the reproductive capacities of three separate age groups of wild-type Ambystoma mexicanum (Dutch strain). Axolotl Newsl. 13:17-20, 1984.

Weijer, C.J., McDonald, S.A. and Durston, A.J. Separation of Dictyostelium discoideum cells into density classes throughout their development and their relationship to the later cell types. Differentiation 28:13-23, 1984.

Weijer, C.J., McDonald, S.A. and Durston, A.J. A frequency difference in optical density oscillations of early Dictyotelium discoideum density classes and its implications for development. Differentiation 28:9-12, 1984.

1983
Bluemink, J.G., Van Maurik, W.A.M., Tertoolen, L.G.J., Van Der Saag, P.T. and De Laat, S.W. Ultrastructural aspects of rapid plasma membrane growth in mitotic neuroblastoma cells. Eur.J.Cell Biol. 32:7-16, 1983.

Bluemink, J.G., Hage, W.J., Van Den Hoef, M.H.F. and Dictus, W.J.A.G. Freeze-fracture electron microscopy of membrane changes in progesterone-induced maturing oocytes and eggs of Xenopus laevis. Eur.J.Cell Biol. 31:85-93, 1983.

Boonstra, J., Moolenaar, W.H., Harrison, P.H., Moed, P., Van Der Saag, P.T. and De Laat, S.W. Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheo-chromocytoma (PC12) cells. J.Cell Biol. 97:92-98, 1983.

Boterenbrood, E.C., Narraway, J.M. and Hara, K. Duration of cleavage cycles and asymmetry in the direction of cleavage waves prior to gastrulation in Xenopus laevis. W.Roux'Arch.Dev.Biol. 192:216-221, 1983.

Chandebois, R. and Faber, J. Automation in animal development; a new theory derived from the concept of cell sociology. In: Monographs in Developmental Biology, edited by Wolsky, A. Basel: Karger, 1983, p. 1-204.

De Laat, S.W., Boonstra, J., Moolenaar, W.H., Mummery, C.L., Van Der Saag, P.T. and Van Zoelen, E.J.J. The plasma membrane as the primary target for the action of growth factors and tumor promoters in development. In: Development in Mammals, edited by Johnson, M.H. Amsterdam: Elsevier, 1983, p. 33-106.

Dorresteyn, A.W.C., Wagemaker, H.A., De Laat, S.W. and Van Den Biggelaar, J.A.M. Dye-coupling between blastomeres in early embryos of Patella vulgata (Mollusca, Gastropoda): its relevance for cell determination. W.Roux'Arch.Dev.Biol. 192:262-269, 1983.

Moolenaar, W.H., Tsien, R.Y., Van Der Saag, P.T. and De Laat, S.W. Na+/H+ exchange, cytoplasmic pH and the action of growth factors in human fibroblasts. Nature 304:645-648, 1983.

Mummery, C.L., Van Den Brink, C.E., Van Der Saag, P.T. and De Laat, S.W. Screening for cytotoxicity in neuroblastoma cells. I. Dependence of growth inhibition on the presence of serum. Toxicol.Lett. 18:201-209, 1983.

Mummery, C.L., Van Der Saag, P.T. and De Laat, S.W. Loss of EGF binding and cation transport response during differentiation of mouse neuroblastoma cells. J.Cell.Biochem. 21:63-75, 1983.

Mummery, C.L., Van Den Brink, C.E., Van Der Saag, P.T. and De Laat, S.W. Screening for cytotoxicity in neuroblastoma cells. II. Growth inhibition: cell death or impaired cell cycle progression? Toxicol.Lett. 18:211-217, 1983.

Nelemans, S.A. Regulation of plasma membrane lipids during proliferation and differentiation of neuroblastoma cells. Thesis, Univ. Utrecht, pp. 1-153, 1983.

Nieuwkoop, P.D. and Sutasurya, L.A. Some problems in the development and evolution of the chordates. In: Development and Evolution, edited by Goodwin, B.C., Holder, N. and Wylie, C.C. Cambridge: Univ.Press, 1983, p. 123-135. Proc. Symp. Brit. Soc. Dev. Biol., Brighton, March-April 1982.

Ubbels, G.A., Hara, K., Koster, C.H. and Kirschner, M. Evidence for a functional role of the cytoskeleton in determination of the dorsoventral axis in Xenopus laevis eggs. J.Embryol.Exp.Morph. 77:15-37, 1983.

Ubbels, G.A., Brom, T.G., Willemsen, H.P. and Van Nunen, J.J.H. The role of gravity in the establishment of the dorso-ventral axis in the developing amphibian embryo. In: Space Biology with Emphasis on Cell and Developmental Biology, edited by Longdon, N. and Melita, O. Cologne: Eur.Space Agency (ESA) Scient.and Techn.Publ., 1983, p. 77-82. Proc. Workshop Noordwijk, March 1983.

Van Dongen, C.J., Hershkowitz, M., Zwiers, H., De Laat, S.W. and Gispen, W.H. Lipid fluidity and phosphoinositide metabolism in brain membranes of aged rats: effects of ACTH1-24. In: Aging of the Brain, edited by Gispen, W.H. and Faber, J. Amsterdam: Elsevier Sci.Publ., 1983, p. 101-114. Proc. 1st Internatn. Tropon Symp. on Brain Aging, Cologne, November 1982; Developments in Neurology, 7.

Van Zoelen, E.J.J., Mummery, C.L., Boonstra, J., Van Der Saag, P.T. and De Laat, S.W. Membrane regulation of the Na+, K+-ATPase during neuroblastoma cell cycle: correlation with protein lateral mobility. J.Cell.Biochem. 21:77-91, 1983.

Verhoeff-de Fremery, R. Diseases in the amphibian facility of the Hubrecht Laboratory (Ambystoma mexicanum, Xenopus laevis, Discoglossus pictus, Rana pipiens, Rana lessonae, Bombina orientalis). In: Proceedings of the First International Colloquium on Pathology of Reptiles and Amphibians, edited by Vago, C. and Matz, G. Angers: Presses Univ., 1983, p. 9-10. Coll. Angers, France, Sept.-Oct. 1982.

Vervoordeldonk, F.J.M. Het houden en kweken van de krekel Gryllus bimaculatus. Biotechniek 22:75-76, 1983.

1982
Boonstra, J., Nelemans, S.A., Feijen, A., Bierman, A.J., Van Zoelen, E.J.J., Van Der Saag, P.T. and De Laat, S.W. Effect of fatty acids on plasma membrane lipid dynamics and cation permeability in neuroblastoma cells. Biochim.Biophys.Acta 692:321-329, 1982.

Boonstra, J., Mummery, C.L., Van Zoelen, E.J.J., Van Der Saag, P.T. and De Laat, S.W. Monovalent cation transport during the cell cycl. Anticancer Res. 2:265-274, 1982.

Boonstra, J., Skaper, S.D. and Varon, S. Regulation of Na+, K+ pump activity by nerve growth factor in chick embryo dorsal root ganglion cells. J.Cell.Physiol. 113:28-34, 1982.

De Laat, S.W., Tertoolen, L.G.J., Van Der Saag, P.T. and Bluemink, J.G. Quantitative analysis of modulations in numerical and lateral distribution of intramembrane particles during the cell cycle of neuroblastoma cells. J.Cell Biol. 96:1047-1055, 1982.

De Laat, S.W., Boonstra, J., Moolenaar, W.H., Mummery, C.L., Van Der Saag, P.T. and Van Zoelen, E.J.J. Cation transport and growth control in neuroblastoma cells in culture. In: Membranes in Growth and Development, edited by Hoffman, J.F., Giebisch, G.H. and Bolis, L. N.Y.: A.Liss, 1982, p. 211-236. Proc. Intern. Conf. on Biol. Membranes, Crans-sur-Sierre, Switzerland, June 1981; Progress in Clin. Biol. Res., 91.

De Laat, S.W. and Van Der Saag, P.T. Modulation of structure and function of the plasma membrane in the cell cycle of neuroblastoma cells. In: Genetic Expression in the Cell Cycle, edited by Padilla, G.M. and McCarty, K.S. N.Y.: Acad.Press, 1982, p. 337-361. Cell Biology, a Series of Monographs.

De Laat, S.W. and Van Der Saag, P.T. The plasma membrane as a regulatory site in growth and differentiation of neuroblastoma cells. Intern.Rev.Cytol. 74:1-54, 1982.

De Laat, S.W. and Moolenaar, W.H. De celmembraan, regelcentrum van groei en ontwikkeling. In: Biofysica; Levende Natuurkunde, edited by Chamalaun, M. and Stavenga, D. Amsterdam: Intermediair, 1982, p. 13-29.

Dorresteyn, A.W.C., Bilinski, S.M., Van Den Biggelaar, J.A.M. and Bluemink, J.G. The presence of gap junctions during early Patella embryogenesis: an electron microscopical study. Dev.Biol. 91:397-401, 1982.

Lawson, K.A. Stage specificity in the mesenchyme requirement of rodent lung epithelium in vitro: a matter of growth control? J.Embryol.Exp.Morph. 74:183-206, 1982.

Luckett, W.P. and Maier, W. Development of deciduous and permanent dentition in Tarsius and its phylogenetic significance. Fol. Primatol. 37:1-36, 1982.

Moolenaar, W.H. Na+/H+ exchange in the action of growth factors. In: Ions, Cell Proliferation and Cancer, edited by Boynton, A.L., McKeehan, W.L. and Whitfield, J.F. N.Y.: Acad.Press, 1982, p. 151-162. Proc. Symp. Lake Placid, N.Y., July 1982.

Moolenaar, W.H., Yarden, Y., De Laat, S.W. and Schlessinger, J. Epidermal growth factor induces electrically silent Na+ influx in human fibroblasts. J.Biol.Chem. 257:8502-8506, 1982.

Moolenaar, W.H., Mummery, C.L., Van Der Saag, P.T. and De Laat, S.W. Rapid ionic events following growth stimulation of neuroblastoma cells. In: Membranes in Tumour Growth, edited by Galeotti, T., Neri, G. and Papa, S. Amsterdam: Elsevier Biomed.Press, 1982, p. 413-418. Proc. Internatn. Workshop on Membranes in Tumour Growth, Rome, June 1982.

Mummery, C.L., Boonstra, J., Van Der Saag, P.T. and De Laat, S.W. Modulations of Na+ transport during the cell cycle of neuroblastoma cells. J.Cell.Physiol. 112:27-34, 1982.

Nieuwkoop, P.D. La détermination et la migration des cellules germinales dans le règne animal. Ann.Biol. 21:37-51, 1982.

Palecek, J., Ubbels, G.A. and Mácha, J. An immunocytochemical method for the visualization of tubulin-containing structures in the egg of Xenopus laevis. Histochemistry 76:527-538, 1982.

Sugimoto, K., Hage, W.J. and Bluemink, J.G. Gap junction formation between normal and reaggregated endoderm cells of Xenopus laevis neurulae. W. Roux' Arch. 191:143-148, 1982.

Van Zoelen, E.J.J., Tertoolen, L.G.J., Boonstra, J., Van Der Saag, P.T. and De Laat, S.W. Effect of external ATP on the plasma membrane permeability and (Na++K+)-ATPase activity of mouse neuroblastoma cells. Biochim.Biophys.Acta 720:223-234, 1982.

Van Zoelen, E.J.J., Tertoolen, L.G.J. and De Laat, S.W. Simple computer method for evaluation of lateral diffusion coefficients from fluorescence photobleaching recovery kinetics. Biophys.J. 42:103-108, 1982.

Verhoeff-de Fremery, R. and Vervoordeldonk, F.J.M. Skin autografts as markers in the toad (Xenopus laevis). Lab.Anim. 16:156-158, 1982.

Yew, D.T. Development of the eyes in Agnatha and Chondrichthyes (Elasmobranchia). Anat.Anz. 151:231-239, 1982.

1981
Bluemink, J.G. and Beetschen, J.C. An ultrastructural study of the maternal effect embryos of the ac/ac mutant of Pleurodeles waltli showing a gastrulation defect. J.Embryol.Exp.Morph. 63:67-74, 1981.

Boonstra, J., Van Der Saag, P.T., Moolenaar, W.H. and De Laat, S.W. Rapid effects of nerve growth factor on the Na+, K+ pump in rat phenochromocytoma cells. Exp.Cell Res. 131:452-455, 1981.

Boonstra, J., Mummery, C.L., Tertoolen, L.G.J., Van Der Saag, P.T. and De Laat, S.W. Characterization of 42K+ and 86Rb+ transport and electrical membrane properties in exponentially growing neuroblastoma cells. Biochim.Biophys.Acta 643:89-100, 1981.

Boonstra, J., Mummery, C.L., Tertoolen, L.G.J., Van Der Saag, P.T. and De Laat, S.W. Cation transport and growth regulation in neuroblastoma cells; modulations of K+ transport and electrical membrane properties during the cell cycle. J.Cell.Physiol. 107:75-83, 1981

De Laat, S.W. and Moolenaar, W.H. De celmembraan, regelcentrum van groei en ontwikkeling. Intermediair 17:15-23, 1981.

De Laat, S.W. Cation transport and growth control in neuroblastoma cells in vitro. In: Annual Report 1980-1981. Stichting voor Biofysica, 1981, p. 218-225.

De Laat, S.W., Tertoolen, L.G.J. and Bluemink, J.G. Quantitative analysis of the numerical and lateral distribution of intramembrane particles in freeze-fractured biological membranes. Eur.J.Cell Biol. 23:273-279, 1981.

Dorresteyn, A.W.C., Van Den Biggelaar, J.A.M., Bluemink, J.G. and Hage, W.J. Electron microscopical investigations of the intercellular contacts during the early cleavage stages of Lumnaea stagnalis (Mollusca,Gastropoda). W. Roux' Arch. 190:215-220, 1981.

Faber, J. Opening address. In: Early Amphibian Development, a Paradigm for Morphogenesis, edited by Faber, J. Leiden: Brill, E.J. 1981, p. 1-4. Symp. Hubrecht Lab., August 1980; org. by Neth. Soc. Dev. Biol., in honour of Prof. P.D. Nieuwkoop, to mark his retirement in 1980 as director of the Hubrecht Laboratory.

Gerhart, J.C., Ubbels, G.A., Black, S.D., Hara, K. and Kirschner, M. A reinvestigation of the role of the grey crescent in axis formation in Xenopus laevis. Nature 292:511-516, 1981.

Luckett, W.P. and Maier, W. Development of deciduous and permanent dentition in Tarsius and its phylogenetic significance. Folia Primatol. 37:1-36, 1981.

Michael, P. A normal table of early development in Bombina orientalis (Boulenger), in relation to rearing temperature. Dev. Growth Diff. 23:149-155, 1981.

Moolenaar, W.H. Functional aspects of plasma membrane studies: growth regulation by ionic fluxes. In: Cell Biological Aspects of Disease; Plasma Membranes and Lysosomes, edited by Daems, W.T., Burger, E.H. and Afzelius, B.A. The Hague: Nijhoff, 1981, p. 27-36. Boerhaave Series, 19.

Moolenaar, W.H., Boonstra, J., Van Der Saag, P.T. and De Laat, S.W. Sodium/proton exchange in mouse neuroblastoma cells. J.Biol.Chem. 256:12883-12887, 1981.

Moolenaar, W.H., Mummery, C.L., Van Der Saag, P.T. and De Laat, S.W. Rapid ionic events and the initiation of growth in serum-stimulated neuroblastoma cells. Cell 23:789-798, 1981.

Mummery, C.L., Boonstra, J., Van Der Saag, P.T. and De Laat, S.W. Modulation of functional and optimal (Na+-K+)ATPase activity during the cell cycle of neuroblastoma cells. J.Cell.Physiol. 107:1-9, 1981.

Rzehak, K., Ubbels, G.A. and Koster, C.H. A method for the enhancement of bi- and trispermic fertilization in eggs of Xenopus laevis. Folia Biol. 29:71-76, 1981.

Ullman, S.L. Sexual differentiation of the gonads in bandicoots (Peramelidae, Marsupialia). In: Development and Function of Reproductive Organs, edited by Byskov, A.G. and Peters, H. Amsterdam: Excerpta Medica, 1981, p. 41-50. Proc. 5th Workshop on the Development and Function of the Reproductive Organs, Copenhagen, July 1981; Intern. Congr. Series, 559.

Van Den Biggelaar, J.A.M., Dorresteyn, A.W.C., De Laat, S.W. and Bluemink, J.G. The role of topographical factors in cell interaction and determination of cell lines in molluscan development. In: International Cell Biology 1980-1981, edited by Schweiger, H.G. Berlin: Springer, 1981, p. 526-538.

Van Der Saag, P.T., Feijen, A., Miltenburg-Vonk, W. and De Laat, S.W. Plasma membrane-mediated effects of extracellular pH on the growth of neuroblastoma cells. Exp.Cell Res. 136:351-358, 1981.

Van Venetië, R., Hage, W.J., Bluemink, J.G. and Verkleij, A.J. Propane jet-freezing: a valid ultra-rapid freezing method for the perservation of temperature dependent lipid phases. J.Microscopy 23:287-292, 1981.

Van Zoelen, E.J.J., Van Der Saag, P.T. and De Laat, S.W. Sources of variation in intermitotic time and their relation to cell cycle kinetics. J.Theor.Biol. 93:1037-1045, 1981.

Van Zoelen, E.J.J., Van Der Saag, P.T. and De Laat, S.W. Family tree analysis of a transformed cell line and the transition probability model for the cell cycle. Exp.Cell Res. 131:395-406, 1981.

Verhoeff-de Fremery, R. Mogelijkheden om de produktie van sperma, onbevruchte en bevruchte eieren van amfibieën te beinvloeden. Biotechniek 20:41-47, 1981.